ArticleAnnals of Saudi medicine
Prevalence of hyponatremia among medically hospitalized patients and associated outcomes: a retrospective cohort study.
Article in Annals of Saudi medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Antidepressants and the risk of hyponatremia: A multi-institutional cohort study using observational medical outcomes partnership-Common Data Model.British journal of clinical pharmacology · 2026Observational
- Furosemide plus oral sodium chloride for syndrome of inappropriate antidiuresis after fluid restriction failure.Clinical kidney journal · 2026Article
- Drug-Induced Hyponatremia Surveillance: A disproportionality analysis based on FAERs database.Pakistan journal of medical sciences · 2026Article
- The role of electrolytes imbalance in determining poor health outcomes in a cohort of older in-patients: the ELECTROHEALTH study.Aging clinical and experimental research · 2026Article
- Effects of oral rehydration solution-based prophylactic sodium supplementation on clinical outcomes in pediatric pneumonia: A randomized controlled trial.World journal of clinical pediatrics · 2025Article
- Urine Electrolyte to Predict Treatment Failure of Fluid Restriction in Syndrome of Inappropriate Antidiuresis: A Prospective Multicenter Study.Kidney360 · 2025Article
- Eight-Year Retrospective Analysis of Mortality in Patients with Moderate to Severe Hyponatremia: A Comprehensive Study.Journal of clinical medicine · 2025Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHyponatremia is a common electrolyte disturbance among hospitalized patients and is linked to increased mortality as well as poor outcomes.
objectivesStudy the prevalence of hyponatremia among medically admitted patients and the outcomes associated with hyponatremia.
designRetrospective cohort.
settingMedical ward at tertiary hospital setting. PATIENTS AND
methodsThe study included adult (≥18 years) hospitalized patients in general medical wards. Three readings of serum sodium level were taken (initial sodium level, nadir during admission, and before discharge). SAMPLE SIZE AND BASIS: The sample size of 350 was determined based on a presumed 35% incidence of hyponatremia among hospitalized patients, with a 5% error margin.
main outcome measuresThe prevalence of hyponatremia among medically hospitalized patients and association with health outcomes including length of hospital stay, inpatient mortality, 90-days readmission and 1-year mortality.
resultsIn this study, 736 patients met the inclusion criteria. Of these, 377 (51.2%) had hyponatremia on admission, increasing to 562 (76.35%) during hospitalization. Mild hyponatremia was observed in 49.6% (n=365), moderate in 13.6% (n=100), and severe in 13.2% (n=97). Severe hyponatremia patients were significantly older (
conclusionHyponatremia was prevalent among medically hospitalized patients and more common among old patients, women, and patients with comorbidities. Hyponatremia was associated with increased length of stay in hospital and increased risk of 90-day re-admission. LIMITATIONS: Single-centre design and retrospective nature.
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