ArticleVirchows Archiv : an international journal of pathology2025
A locally infiltrative juxtaglomerular cell tumor with unusual histologic features.
Article in Virchows Archiv : an international journal of pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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Corrections and comments
- Erratum issued
Authors and funding
3 authors.
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Abstract
Juxtaglomerular cell tumor (JGCT) is an exceptionally rare renal tumor with a predominantly benign clinical course and classically bland histology. It commonly presents in young adults and manifests as hypertension related to renin secretion. We report a JGCT initially thought to be a renal cell carcinoma. It was unique because of its size, high-grade histologic features and locally infiltrative nature-extension into the renal pelvis. It is unclear whether features such as tumor necrosis, pleomorphism and increased proliferative activity are predictive of metastatic potential and/or locally aggressive behavior. Clinical follow-up may be warranted in such cases.
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