ArticleContact dermatitis2025
Contents of sensitising rubber accelerators in disposable rubber gloves: A Copenhagen market survey.
Article in Contact dermatitis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- European Society of Contact Dermatitis Guideline for Diagnostic Patch Testing-Recommendations on Best Practice (Update 2026).Contact dermatitis · 2026Guideline
- Prevalence of Contact Allergy to Rubber Accelerators From the European Baseline Series in Dermatitis Patients: A Systematic Review and Meta-Analysis.Contact dermatitis · 2025Pooled it
- Patch Test Results With the European Baseline Series, 2021/2022-Joint European Results of the ESSCAContact dermatitis · 2026Article
- Positive Patch Test Reactions to Dental Rubber Dams and Zinc Ethylphenyldithiocarbamate in a Patient Sensitised to Thiurams and Other Carbamates.Contact dermatitis · 2026Article
- Evaluation of Patients With Positive Patch Test Reactions to Rubber Additives: A Retrospective Study From Turkey Between 1996 and 2023.Contact dermatitis · 2025Article
- The Carba Mix-In Vitro Investigations of Potential Cocktail Effects in Patch Tests With Rubber Allergens.Contact dermatitis · 2025Article
- Thresholds for Contact Allergy to a Rubber Accelerator: TETD-Determined by Serial Dilution Patch Testing and a Simulated Glove-Use Model.Contact dermatitis · 2025Article
- Contents of sensitising rubber accelerators in disposable rubber gloves: A Copenhagen market survey.Contact dermatitis · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundRubber gloves contain rubber accelerators that may cause contact allergy. The content of sensitising rubber accelerators in contemporary rubber gloves is not well known.
objectivesIdentify and quantify the content of rubber accelerators in disposable rubber gloves.
methodsFifty-one gloves of 49 different brands were collected. Forty-eight of the gloves were disposable and three re-usable. The gloves were analysed for their content of sensitising rubber accelerators, that is, zinc dithiocarbamates, thiurams, thiazoles/benzothiazoles, diphenylguanidine, and thioureas by high-performance liquid chromatography.
resultsRubber accelerators were identified in 43/48 (90%) of the disposable gloves. In total, 39 gloves contained zinc dibutyldithiocarbamate (ZDBC) (0.18-1.96 mg/g), 34 zinc diethyldithiocarbamate (ZDEC) (0.032-2.78 mg/g), three zinc dibenzyldithiocarbamate (0.65-1.4 mg/g), one zinc dimethyldithiocarbamate (0.23 mg/g), and one 1,3-diphenylguanidine (0.21 mg/g). 2-cyanoethyl dimethyldithiocarbamate (CEDMC) was identified in three gloves (<0.052 mg/g). The one glove labelled as accelerator free contained ZDBC (1.07 mg/g). Only few glove packages had the specific content of rubber accelerators labelled.
conclusionsThe most frequent rubber accelerators in rubber gloves are ZDEC and ZDBC. Accelerator-free gloves may contain rubber accelerators. Full labelling of rubber gloves is needed and producers should be sure not to falsely claim that the rubber gloves are free of rubber accelerators.
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Registered trials
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