Evidence map›Paper›PMID 39367248›Full record

ReviewNature reviews. Chemistry2024

Accessing monomers from lignin through carbon-carbon bond cleavage.

Chad T Palumbo, Erik T Ouellette, Jie Zhu, Yuriy Román-Leshkov, Shannon S Stahl, Gregg T Beckham

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  11. Review
  12. Nanozymes for Energy and Environmental Sustainability.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. High enzyme promiscuity in lignin degradation mechanisms inApplied and environmental microbiology · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chad T PalumboRenewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO, USA.ORCID 0000-0001-6436-4602
Erik T OuelletteRenewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO, USA.ORCID 0000-0003-2138-6259
Jie ZhuDepartment of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID 0000-0002-9152-9326
Yuriy Román-LeshkovDepartment of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. yroman@mit.edu.ORCID 0000-0002-0025-4233
Shannon S StahlDepartment of Chemistry. Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA. stahl@chem.wisc.edu.ORCID 0000-0002-9000-7665
Gregg T BeckhamRenewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO, USA. gregg.beckham@nrel.gov.ORCID 0000-0002-3480-212X

Funding

US Department of Energy DE-AC36-08GO28308US Department of Energy DEFG02-05ER15690
6 · The paper itself

Abstract

Lignin, the heterogeneous aromatic macromolecule found in the cell walls of vascular plants, is an abundant feedstock for the production of biochemicals and biofuels. Many valorization schemes rely on lignin depolymerization, with decades of research focused on accessing monomers through C-O bond cleavage, given the abundance of β-O-4 bonds in lignin and the large number of available C-O bond cleavage strategies. Monomer yields are, however, invariably lower than desired, owing to the presence of recalcitrant C-C bonds whose selective cleavage remains a major challenge in catalysis. In this Review, we highlight lignin C-C cleavage reactions, including those of linkages arising from biosynthesis (β-1, β-5, β-β and 5-5) and industrial processing (5-CH

Indexed as

CarbonLigninBiocatalysisCatalysisCarbonLignin

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.