Evidence map›Paper›PMID 39367231›Full record

ArticleAesthetic plastic surgery2025

Nipple-Areola Complex Reconstruction Using FixNip NRI Implant after Mastectomy: An Innovative Technique.

Serena Iacovelli, Giuseppe De Palma, Valerio De Santis, Daniela Anna Cutrignelli, Andrea Armenio, Samantha Bove, Maria Colomba Comes, Annarita Fanizzi, Elsa Vitale, Raffaella Massafra and 1 more

Erratum issuedAbstract readCase Reports
In one paragraph

Article in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Serena Iacovelli *Scientific Directorate, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
Giuseppe De Palma *Institutional BioBank, Experimental Oncology and Biobank Management Unit, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy. g.depalma@oncologico.bari.it.ORCID 0000-0002-6108-096X
Valerio De SantisPlastic and Reconstructive Surgery Unit, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy. v.desantis@oncologico.bari.it.
Daniela Anna CutrignelliPlastic and Reconstructive Surgery Unit, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
Andrea ArmenioPlastic and Reconstructive Surgery Unit, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
Samantha BoveBiostatistics and Bioinformatic Lab, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
Maria Colomba ComesBiostatistics and Bioinformatic Lab, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
Annarita FanizziBiostatistics and Bioinformatic Lab, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
Elsa VitaleScientific Directorate, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
Raffaella MassafraBiostatistics and Bioinformatic Lab, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
Cosmo Maurizio RessaPlastic and Reconstructive Surgery Unit, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.

Funding

Ricerca Corrente 2024” from the Italian Ministry of Health
6 · The paper itself

Abstract

backgroundNipple-areolar complex reconstruction is the final stage of breast reconstruction, and it improves quality of life in patients with post-mastectomy breast cancer. We present a case of a patient with breast cancer underwent breast reconstruction and subsequent nipple-areolar complex reconstruction with an innovative biocompatible smooth silicone implant specially designed for a long-lasting restoration of the nipple-areola complex called FixNip NRI. However, to our knowledge, nipple-areolar complex reconstruction with FixNip was not previously reported. INNOVATIVE TECHNIQUE: We present an emerging technique applied on a patient with breast cancer treated with skin-sparing mastectomy and with immediate breast reconstruction using an expander and then exchanged expander to breast implant. FixNip nipple reconstruction implant is implanted for the reconstruction of the areola-nipple complex with local-regional anaesthesia. She did not develop any postoperatively short-term or long-term complications, and her nipple slowly underwent to a gradual and better definition of its profile.

conclusionThis new approach regarding the reconstruction of the nipple-areola complex seems to be very promising in relation to both the degree of aesthetic satisfaction of patients and the ease of use by surgeons. LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Breast ImplantationBreast ImplantsBreast NeoplasmsMammaplastyMastectomyNipplesEstheticsFemaleFollow-Up StudiesHumansMiddle AgedProsthesis DesignRisk AssessmentTreatment OutcomeAreolaFixNipMastectomyNippleReconstruction

Identifiers

PMID39367231
PMCPMC11965199

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.