Evidence map›Paper›PMID 39367184›Full record

ArticleThe international journal of cardiovascular imaging2024

Diagnosing myocardial ischemia of obstructive coronary artery disease using dynamic computed tomography myocardial perfusion imaging: optimization of relative myocardial blood flow ratio.

Weifang Kong, Bingzhu Long, Fang Li, Lan Shang, Xinyue Chen, Aamer Chughtai

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The international journal of cardiovascular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Weifang KongDepartment of Radiology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China. kongweifang@med.uestc.edu.cn.ORCID http://orcid.org/0009-0005-8541-8135
Bingzhu LongSchool of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Fang LiDepartment of Radiology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Lan ShangDepartment of Radiology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Xinyue ChenCT collaboration, Siemens Healthineers, Chengdu, China.
Aamer ChughtaiDepartment of Radiology, Cleveland Clinic, Cleveland, USA. Chughta@ccf.org.

Funding

Sichuan Provincial Cadre Health Research Project No. 2020-225, No. 2021-230Sichuan Science and Technology Program No. 2022YFS0075
6 · The paper itself

Abstract

purposeTo compare the diagnostic efficacy of different relative myocardial blood flow (MBF) ratios in computed tomography perfusion (CTP) for myocardial ischemia in patients with obstructive coronary artery disease (CAD).

methodsBetween October 2020 and March 2024, patients with suspected or known obstructive CAD who underwent CTP + coronary computed tomography angiography and invasive coronary angiography/fractional flow reserve were retrospectively selected. Patients and vessels were categorized into ischemia and non-ischemia groups. The diagnostic efficacies of the three relative MBF ratios were compared in patients with obstructive CAD.

resultsThis study included 48 patients (144 vessels). Notably, 34 of the 48 patients (70.83%) and 49 of the 144 vessels (34.03%) were considered to have myocardial ischemia. The area under the curve of Ratio-hi (0.944, 95% confidence interval: 0.893-0.976) was higher than those of Ratio-av, Ratio-Q3, and MBF-lowest; However, no statistical differences were found (P>0.005). The cutoff value for detecting Ratio-hi was 0.667, and the sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy were 91.8%, 83.2%, 75%, 95.24%, and 86.81%, respectively.

conclusionRelative MBF ratios, especially Ratio-hi, demonstrated excellent performance and exhibited greater robustness in diagnosing myocardial ischemia in patients with obstructive CAD.

Indexed as

Computed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseFractional Flow Reserve, MyocardialMyocardial Perfusion ImagingPredictive Value of TestsAgedBlood Flow VelocityCoronary CirculationCoronary StenosisFemaleHumansMaleMiddle AgedMyocardial IschemiaReproducibility of ResultsComputed tomographyCoronary artery diseaseMyocardial blood flowMyocardial ischemiaMyocardial perfusion

Identifiers

PMID39367184
PMCPMC11618156

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.