Evidence map›Paper›PMID 39367177›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2024

Age- and gender-dependent impact of titanium vertebral augmentation implants combined with cementing on subsequent vertebral fracture incidence: A comparative study with cementing alone.

Chien-Ting Sun, Yi-Shan Yang, Chen-Ling Lan, Huy Minh Tran, Tuan Anh Pham, Yung-Hsiao Chiang, Chien-Min Lin, Yu-Kai Su, Yi-Chen Hsieh, Jiann-Her Lin

Erratum issuedAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. [Analysis of demographic and clinical characteristics of 744 inpatients with osteoporotic vertebral compression fractures].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Chien-Ting Sun *Department of Neurosurgery, Taipei Medical University Hospital, Taipei, Taiwan.
Yi-Shan Yang *Department of Neurosurgery, Taipei Medical University Hospital, Taipei, Taiwan.
Chen-Ling LanDivision of Neurosurgery, Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Huy Minh TranDepartment of Neurosurgery, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Tuan Anh PhamDepartment of Neurosurgery, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Yung-Hsiao ChiangDivision of Neurosurgery, Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Chien-Min LinDepartment of Neurosurgery, Ministry of Health and Welfare Shuang-Ho Hospital, New Taipei City, Taiwan.
Yu-Kai SuDepartment of Neurosurgery, Ministry of Health and Welfare Shuang-Ho Hospital, New Taipei City, Taiwan.
Yi-Chen HsiehCollege of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Jiann-Her LinDivision of Neurosurgery, Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. jiannher@me.com.ORCID 0000-0002-7255-741X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare vertebroplasty (VP) and kyphoplasty (KP) with a titanium implantable vertebral augmentation device (TIVAD) in symptomatic subsequent vertebral compression fracture (SVCF) incidence among osteoporotic vertebral compression fracture (OVCF) patients stratified by age and sex.

methodsThis retrospective cohort study involved OVCF patients aged ≥ 50, who underwent KP with TIVAD or VP in our hospital from 2014 to 2019. Subgroup analysis was conducted to evaluate the efficacy of KP with TIVAD and VP in patients stratified by age and sex.

resultsThe study included 472 patients (VP group: 303; TIVAD group: 169). SVCF incidence rates were 15.2% for VP group and 14.8% for TIVAD group (P = 0.87). In subgroup analysis, TIVAD group showed significantly lower SVCF incidence than VP group in women aged 50-70 (2.1% vs 14.3%; P = 0.03) and had significantly higher SVCF incidence than VP group in women aged > 70 (24.2% vs 13.1%; P = 0.02). In men, adjacent SVCF incidence was significantly lower in TIVAD group than VP group (0% vs 14.1%; P = 0.03).

conclusionCompared to VP, TIVAD is associated with lower symptomatic SVCF rate in men and younger women aged 50-70 but not in older women aged > 70. Age and gender may influence SVCF incidence. LEVEL OF EVIDENCE: Diagnostic: individual cross-sectional studies with consistently applied reference standard and blinding.

Indexed as

Fractures, CompressionKyphoplastyOsteoporotic FracturesSpinal FracturesTitaniumVertebroplastyAgedAged, 80 and overAge FactorsBone CementsFemaleHumansIncidenceMaleMiddle AgedProstheses and ImplantsBone CementsTitaniumOsteoporotic vertebral compression fractureSubsequent vertebral compression fractureTitanium implantable vertebral augmentation deviceVertebroplasty

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.