Evidence map›Paper›PMID 39367140›Full record

ArticleEuropean journal of pediatrics2024

The economic burden of varicella among children in France: a caregiver survey.

Salome Samant, Hervé Haas, Joana Santos, David R Mink, Richard Pitman, Tanaz Petigara, Manjiri Pawaskar

Abstract read
In one paragraph

Article in European journal of pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Salome SamantMerck & Co., Inc, Merck Research Laboratories (MRL), Rahway, NJ, USA. Salome.samant@merck.com.ORCID http://orcid.org/0000-0001-6176-0677
Hervé HaasPediatric Department, Princess Grace Hospital, Monaco, Monaco.ORCID http://orcid.org/0009-0008-3364-4298
Joana SantosICON Clinical Research, Global Health Economics and Outsomes Research, Lisbon, Portugal.
David R MinkICON Clinical Research, Global Health Economics and Outsomes Research, Novato, CA, USA.
Richard PitmanICON Clinical Research, Global Health Economics and Outsomes Research, Reading, UK.
Tanaz PetigaraMerck & Co., Inc, Merck Research Laboratories (MRL), Rahway, NJ, USA.ORCID http://orcid.org/0000-0001-8366-5101
Manjiri PawaskarMerck & Co., Inc, Merck Research Laboratories (MRL), Rahway, NJ, USA.ORCID http://orcid.org/0000-0001-8009-805X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To estimate the economic burden of varicella among children in France from family and societal perspectives. We conducted an online cross-sectional survey of caregivers of 185 French children (≤ 17 years) diagnosed with varicella in the previous six weeks. Data collected included varicella-related healthcare resource use, out-of-pocket costs, missed school days, and workdays missed by either parents or other caregivers. Mean and median direct and indirect costs (2022 Euros) were calculated using survey data and published literature. The annual societal burden of pediatric varicella in France was estimated. Of the 185 children, 95.1% had ≥ 1 outpatient visit, 10.3% had ≥ 1 emergency room visit, and 2.2% were hospitalized. The median [interquartile range, IQR] number of outpatient visits/child was 1.0 [1.0 - 2.0]. The median length of hospital stay among those hospitalized (n = 4) was 5.0 [3.5 - 6.5] days. Caregivers of 185 children missed a median of 2.0 [0 - 5.0] workdays; 113 families (61.1%) had ≥ 1 parent miss work. A median of 5.0 [3.0 - 7.0] school days were missed by 170 children who attended preschool or school. The median direct out-of-pocket cost to the family was €30.0 [€17.0 - €60.0]. The median [IQR] societal costs per varicella case were €455.2 [€70.5 - €1013.5]; the median [IQR] direct and indirect costs per child were €60.8 [€39.0 - €102.7] and €364.7 [€0.0 - €911.7] respectively. The annual societal burden of varicella among children in France was estimated to be €450,427,578 (95% CI: €357,144,618 - €543,710,538), with indirect costs accounting for 85%.

conclusionsA substantial economic burden is associated with pediatric varicella in France, primarily due to the productivity loss among caregivers. WHAT IS KNOWN: • Although varicella is considered a mild disease, it poses a significant burden on caregivers and society. Our study aimed to estimate the economic burden of varicella among children in France from family and societal perspectives to support policymakers in understanding the value of UVV in France. WHAT IS NEW: • We conducted an online survey of caregivers of 185 French children (≤17 years) diagnosed with varicella and collected data on varicella-related healthcare resource use, missed school days and workdays. Our study estimated annual societal burden of pediatric varicella in France. Out of 185 children with varicella, most (95.1%) had at least one outpatient visit, 10.3% had at least one emergency room visit, and 2.2% were hospitalized. 61.1% of parents with sick child, missed work and median productivity loss was 2.0 workdays. Additionally, 170 children who attended school or preschool missed a median of 5.0 school days. • The societal burden of pediatric varicella in France was estimated to be €450,427,578 (95% CI, €357,144,618 - €543,710,538), with indirect costs accounting for 85%. Pediatric varicella is associated with a substantial economic burden in France, primarily due to high productivity losses among parents and caregivers.

Indexed as

CaregiversChickenpoxCost of IllnessHealth ExpendituresAbsenteeismAdolescentChildChild, PreschoolCross-Sectional StudiesFemaleFranceHealth Care CostsHospitalizationHumansInfantMaleBurden of diseaseCostFranceProductivity lossVaccineVaricella

Identifiers

PMID39367140
PMCPMC11527928

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.