ArticleScientific reports2024
Impact of photobiomodulation therapy on pro-inflammation functionality of human peripheral blood mononuclear cells - a preliminary study.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The trial behind it
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Who cites it
10 citing papers in PubMed.
- Effect of photobiomodulation therapy on regulating reparative processes of chronic wounds at the inflammation stageBiomedica : revista del Instituto Nacional de Salud · 2026Article
- Analgesic outcomes of 650 nm versus 810 nm diode laser photobiomodulation after dental implant placement in a randomized controlled trial.Scientific reports · 2026Article
- Assessment of Dose-Dependent Effects of 1064 nm Photobiomodulation Therapy on Tenocyte- and Bursa-Derived Cell Proliferation In Vitro.Journal of clinical medicine · 2026Article
- Photobiomodulation and Low-Level Laser Therapy as Complementary Strategies in Diabetes Treatment.International journal of molecular sciences · 2026Review
- From light to healing: photobiomodulation therapy in medical disciplines.Journal of translational medicine · 2025Review
- Photobiomodulation stimulates mitochondrial function and cell proliferation in meniscus-derived stem cells (MeSCs) via activation of TRPV1 channel.Scientific reports · 2025Article
- Photostimulation of skull bone marrow modulates neuroimmunity in sepsis-associated encephalopathy via the skull bone marrow-dura mater-brain axis.Journal of neuroinflammation · 2025Article
- Dosimetric parameters and clinical outcomes of photobiomodulation in diabetic neuropathy: a concise review.Lasers in medical science · 2025Review
- Photobiomodulation Meets Mechanotransduction: Immune-Stromal Crosstalk in Orthodontic Remodeling.Biomedicines · 2025Review
- Experimental Investigation of the Effects of Photobiomodulation Therapy on the Viability, Migration, and Gene Expression of Human Gingival Fibroblasts.Journal of lasers in medical sciences · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Research into the efficacy of photobiomodulation therapy (PBMT) in reducing inflammation has been ongoing for years, but standards for irradiation methodology still need to be developed. This study aimed to test whether PBMT stimulates in vitro human peripheral blood mononuclear cells (PBMCs) to synthesize pro-inflammatory cytokines, including chemokines. PBMCs were irradiated with laser radiation at two wavelengths simultaneously (λ = 808 nm in continuous emission and λ = 905 nm in pulsed emission). The laser radiation energy was dosed in one dose as a whole (5 J, 15 J, 20 J) or in a fractionated way (5 J + 15 J and 15 J + 5 J) with a frequency of 500, 1,500 and 2,000 Hz. The surface power densities were 177, 214 and 230 mW/cm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.