Evidence map›Paper›PMID 39367053›Full record

ArticleMolecular psychiatry2025

David Matuskey, Yanghong Yang, Mika Naganawa, Sheida Koohsari, Takuya Toyonaga, Paul Gravel, Brian Pittman, Kristen Torres, Lauren Pisani, Caroline Finn and 15 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Assessment of noninvasive quantification of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Detection of Focal Lesions in Epilepsy with [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Emerging roles for E3 ubiquitin ligases in neural development and disease.Frontiers in cell and developmental biology · 2025
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

David MatuskeyDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA. david.matuskey@yale.edu.ORCID 0000-0001-7508-6572
Yanghong YangDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Mika NaganawaDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.ORCID 0000-0002-4408-2621
Sheida KoohsariDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Takuya ToyonagaDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Paul GravelDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Brian PittmanDepartment of Psychiatry, Yale University, New Haven, CT, USA.
Kristen TorresDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Lauren PisaniChild Study Center, Yale University, New Haven, CT, USA.
Caroline FinnChild Study Center, Yale University, New Haven, CT, USA.
Sophie Cramer-BenjaminChild Study Center, Yale University, New Haven, CT, USA.ORCID 0000-0001-5586-4111
Nicole HermanChild Study Center, Yale University, New Haven, CT, USA.ORCID 0000-0001-8942-6857
Lindsey H RosenthalChild Study Center, Yale University, New Haven, CT, USA.ORCID 0000-0002-7154-5919
Cassandra J FrankeChild Study Center, Yale University, New Haven, CT, USA.
Bridget M WalickiChild Study Center, Yale University, New Haven, CT, USA.ORCID 0009-0002-9223-2492
Irina EsterlisDepartment of Psychiatry, Yale University, New Haven, CT, USA.ORCID 0000-0001-6293-1458
Patrick SkosnikDepartment of Psychiatry, Yale University, New Haven, CT, USA.
Rajiv RadhakrishnanDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.ORCID 0000-0002-8220-655X
Julie M WolfChild Study Center, Yale University, New Haven, CT, USA.
Nabeel NabulsiDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.ORCID 0000-0001-8129-0051
Jim RopchanDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Yiyun HuangDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Richard E CarsonDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.ORCID 0000-0002-9338-7966
Adam J NaplesCenter for Brain and Mind Health, Yale University, New Haven, CT, USA.
James C McPartlandCenter for Brain and Mind Health, Yale University, New Haven, CT, USA. james.mcpartland@yale.edu.ORCID 0000-0002-2570-0746

Funding

Depression and accelerated brain aging: A PET imaging studyR01MH118728 · NIMH · YALE UNIVERSITY · PI ESTERLIS, IRINA, PIETRZAK, ROBERT H · 2019 to 2024
$5.6M
Multimodel Assessment of Social Process Systems across Neurodevelopmental DisordersR01MH107426 · NIMH · YALE UNIVERSITY · PI MCPARTLAND, JAMES CHARLES, SRIHARI, VINOD H. · 2015 to 2017
$651k
Social-communicative deficits in Autism Spectrum Disorder as measured by mGluR5 positron emission tomographyR21MH113955 · NIMH · YALE UNIVERSITY · PI MATUSKEY, DAVID A, MCPARTLAND, JAMES CHARLES · 2018 to 2019
$461k
NIMH NIH HHS R01 MH107426NIMH NIH HHS R01 MH118728NIMH NIH HHS R21 MH113955
6 · The paper itself

Abstract

The neural bases of autism are poorly understood at the molecular level, but evidence from animal models, genetics, post-mortem studies, and single-gene disorders implicate synaptopathology. Here, we use positron emission tomography (PET) to assess the density of synapses with synaptic vesicle glycoprotein 2A (SV2A) in autistic adults using

Indexed as

Autistic DisorderSynapsesAdultBrainCarbon RadioisotopesFemaleHumansMaleMembrane GlycoproteinsNerve Tissue ProteinsPositron-Emission TomographyPyridinesPyrrolidinonesYoung Adult1-((3-(methylpyridin-4-yl)methyl)-4-(3,4,5-trifluorophenyl)pyrrolidin-2-oneCarbon RadioisotopesMembrane GlycoproteinsNerve Tissue ProteinsPyridinesPyrrolidinonesSV2A protein, human

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.