Evidence map›Paper›PMID 39366975›Full record

ArticleScientific data2024

A multicenter dataset for lymph node clinical target volume delineation of nasopharyngeal carcinoma.

Xiangde Luo, Wenjun Liao, Yue Zhao, Youjing Qiu, Jinfeng Xu, Yuan He, Hui Huang, Lu Li, Shichuan Zhang, Jia Fu and 2 more

Abstract readDatasetMulticenter Study
In one paragraph

Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiangde LuoDepartment of Radiation Oncology, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital and Institute. Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, China.ORCID 0000-0001-8574-0005
Wenjun LiaoDepartment of Radiation Oncology, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital and Institute. Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, China. liao_wj2023@uestc.edu.cn.ORCID 0000-0002-8907-7615
Yue ZhaoDepartment of Radiation Oncology, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital and Institute. Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, China.ORCID 0000-0002-6586-6062
Youjing QiuDepartment of Radiation Oncology, Daguan Hospital of Chengdu Jinjiang, Chengdu, China.
Jinfeng XuDepartment of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yuan HeDepartment of Radiation Oncology, The First Affiliated Hospital of University of Science and Technology of China, Hefei, China.
Hui HuangCancer center, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Lu LiDepartment of Radiation Oncology, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital and Institute. Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, China.
Shichuan ZhangDepartment of Radiation Oncology, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital and Institute. Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, China.
Jia FuSchool of Mechanical and Electrical Engineering, University of Electronic Science and Technology of China, Chengdu, China.ORCID 0000-0003-4216-0064
Guotai WangSchool of Mechanical and Electrical Engineering, University of Electronic Science and Technology of China, Chengdu, China.ORCID 0000-0002-8632-158X
Shaoting ZhangSchool of Mechanical and Electrical Engineering, University of Electronic Science and Technology of China, Chengdu, China.ORCID 0000-0002-8719-448X

Funding

Department of Science and Technology of Sichuan Province (Sichuan Provincial Department of Science and Technology) 2023NSFSC1852Health Department of Sichuan Province (Sichuan Province Department of Health) 2023-803National Natural Science Foundation of China (National Science Foundation of China) 82203197
6 · The paper itself

Abstract

The deep learning (DL)-based prediction of accurate lymph node (LN) clinical target volumes (CTVs) for nasopharyngeal carcinoma (NPC) radiotherapy (RT) remains challenging. One of the main reasons is the variability of contours despite standardization processes by expert guidelines in combination with scarce data sharing in the community. Therefore, we retrospectively generated a 262-subjects dataset from four centers to develop the DL models for LN CTVs delineation. This dataset included 440 computed tomography images from different scanning phases, disease stages and treatment strategies. Three clinical expert boards, each comprising two experts (totalling six experts), manually delineated six basic LN CTVs on separate cohorts as the ground truth according to LN involvement and clinical requirements. Several state-of-the-art segmentation algorithms were evaluated on this benchmark, showing promising results for LN CTV segmentation. In conclusion, this work built a multicenter LN CTV segmentation dataset, which may be the first dataset for automatic LN CTV delineation development and evaluation, serving as a benchmark for future research.

Indexed as

Lymph NodesNasopharyngeal CarcinomaNasopharyngeal NeoplasmsDeep LearningHumansRetrospective StudiesTomography, X-Ray Computed

Identifiers

PMID39366975
PMCPMC11452638

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.