ArticleBMJ open diabetes research & care2024
Ethnic-specific oral glucose tolerance (OGTT) phenotypes in women with hyperglycemia in pregnancy.
Article in BMJ open diabetes research & care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Ethnic Differences in Pregnancy Complications Among Women with Gestational Diabetes.Medical sciences (Basel, Switzerland) · 2026Article
- Potential Impact of Revising the Diagnostic Criteria for Gestational Diabetes on Maternal Pregnancy and Infant Perinatal Outcomes.Journal of diabetes · 2026Article
- Feasibility of using OGTT 1-h PG as a diagnostic criterion for diabetes and pre-diabetes.BMJ open diabetes research & care · 2026Article
- Ahmedabad declaration: A framework to combat growing epidemic of young-onset type 2 diabetes in Asia.Diabetes & metabolic syndrome · 2025Review
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3 authors.
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Abstract
introductionEthnic differences associated with oral glucose tolerance test (OGTT) phenotypes is less studied in Southeast Asian ethnicities, especially in women with hyperglycemia in pregnancy (HIP). RESEARCH DESIGN AND
methodsWe retrospectively examined 3027 women at KK Women's and Children's Hospital in 2019. Of these, 508 (16.8%) women were diagnosed with HIP using the IADPSG (International Association of Diabetes and Pregnancy Study Groups) criteria at 24-28 weeks. OGTT phenotypes were classified into four mutually exclusive groups based on abnormal plasma glucose at (1) 0 hour only; (2) 1 hour only; (3) 2 hour only; (4) ≥2 timepoints (reference). Multinomial logistic regression was used to examine the association between ethnicity and OGTT phenotypes, adjusting for maternal age, parity, and first-trimester body mass index.
resultsOverall HIP prevalence was 16.8%, highest among Indians (20.5%), then Chinese (18.3%) and Malays (14.2%). Indians (relative risk ratio (RRR) 3.05) and Chinese (RRR 2.33) were at higher risk of displaying a fasting-only phenotype compared with Malays. Chinese were at increased risk of displaying a 2-hour postprandial phenotype with an RRR of 2.88 as compared with Malays.
conclusionsUnique OGTT phenotypes exist across ethnic groups among women who developed HIP in a multi-ethnic Asian population.
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