Evidence map›Paper›PMID 39365983›Full record

ArticleExperimental physiology2025

Vascular limitations in blood pressure regulation with age in women: Insights from exercise and acute cardioselective β-blockade.

Matthew J Studinski, Christine Bowlus, James A Pawelczyk, Jocelyn M Delgado Spicuzza, Jigar Gosalia, Swapan Mookerjee, Matthew D Muller, Jason Fragin, David N Proctor

Abstract read
In one paragraph

Article in Experimental physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Matthew J StudinskiIntegrative and Biomedical Physiology, Intercollege Graduate Degree Program, The Pennsylvania State University, University Park, Pennsylvania, USA.
Christine BowlusDepartment of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, USA.
James A PawelczykIntegrative and Biomedical Physiology, Intercollege Graduate Degree Program, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID 0000-0002-1470-0652
Jocelyn M Delgado SpicuzzaIntegrative and Biomedical Physiology, Intercollege Graduate Degree Program, The Pennsylvania State University, University Park, Pennsylvania, USA.
Jigar GosaliaDepartment of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, USA.
Swapan MookerjeeDepartment of Health and Exercise Science, Commonwealth University of Pennsylvania, Bloomsburg, Pennsylvania, USA.
Matthew D MullerSchool of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.ORCID 0000-0002-7411-8816
Jason FraginPenn State Heart and Vascular Institute, Penn State College of Medicine, Hershey, Pennsylvania, USA.
David N ProctorIntegrative and Biomedical Physiology, Intercollege Graduate Degree Program, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID 0000-0002-4691-4575

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Research Training in Physiological Adaptations to StressT32GM108563 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI CANTORNA, MARGHERITA T, KORZICK, DONNA HOPE · 2014 to 2023
$2.2M
Integrative Analysis of Metabolic Phenotypes (IAMP) Predoctoral Training ProgramT32DK120509 · NIDDK · PENNSYLVANIA STATE UNIVERSITY, THE · PI PATTERSON, ANDREW, PERDEW, GARY H. · 2020 to 2024
$781k
Novel Therapies to Improve Cardiac and Skeletal Muscle O2 Supply-Demand Mismatch in Older Adults with Peripheral Arterial DiseaseR21AG054940 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI PROCTOR, DAVID N · 2018 to 2019
$429k
National Institutes of Health R21AG054940National Institutes of Health T32DK120509National Institutes of Health T32GM108563NCATS NIH HHS UL1 TR002014NIA NIH HHS R21 AG054940NIDDK NIH HHS T32 DK120509NIGMS NIH HHS T32 GM108563
6 · The paper itself

Abstract

Younger women rely on altering cardiac output (

Indexed as

Blood PressureExercisePropanolaminesAdrenergic beta-1 Receptor AntagonistsAdrenergic beta-AntagonistsAdultAgedAge FactorsAgingCardiac OutputCross-Over StudiesFemaleHeart RateHumansMiddle AgedYoung AdultAdrenergic beta-1 Receptor AntagonistsAdrenergic beta-AntagonistsesmololPropanolaminesageingcardiovascularesmololexercise haemodynamicswomen

Identifiers

PMID39365983
PMCPMC11689121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.