Evidence map›Paper›PMID 39365777›Full record

ArticlePloS one2024

Pain after laparoscopic endometriosis-specific vs. hysterectomy surgeries: A retrospective cohort analysis.

Yael Yagur, Offra Engel, Rachel Burstein, Justin Bsharat, Omer Weitzner, Yair Daykan, Zvi Klein, Ron Schonman

Abstract readComparative Study
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yael YagurMeir Medical Center, Department of Obstetrics and Gynecology, Affiliated with the Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Offra EngelMeir Medical Center, Department of Obstetrics and Gynecology, Affiliated with the Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.ORCID 0000-0001-9481-0773
Rachel BursteinMeir Medical Center, Department of Obstetrics and Gynecology, Affiliated with the Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Justin BsharatSchool of Medicine, New York State/American Program of Tel Aviv University, Tel Aviv, Israel.
Omer WeitznerMeir Medical Center, Department of Obstetrics and Gynecology, Affiliated with the Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Yair DaykanMeir Medical Center, Department of Obstetrics and Gynecology, Affiliated with the Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Zvi KleinMeir Medical Center, Department of Obstetrics and Gynecology, Affiliated with the Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Ron SchonmanMeir Medical Center, Department of Obstetrics and Gynecology, Affiliated with the Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate pain perception and analgesic use between patients who underwent endometriosis-specific laparoscopic surgery compared to laparoscopic hysterectomy. MATERIAL AND

methodsThis retrospective cohort study included women diagnosed with endometriosis who underwent laparoscopic surgery from 1/2019 to 11/2022. The control group consisted of premenopausal women who underwent laparoscopic hysterectomy, which was considered a similarly extensive surgery. Demographics, preoperative and post-operative data were compared between groups. Post-operative pain scores on a visual analogue scale (VAS) between 0 (no pain) and 10 (worst pain) were compared between groups for each post-operative day (POD). Standard pain relief analgesia on POD 0-1 included fixed intravenous treatment with paracetamol and intramuscular diclofenac. The need for additional analgesics (morphine or dipyrone) beyond the standard pain relief protocol was compared between groups.

resultsAmong 200 patients who underwent laparoscopic surgery, 100 (50%) were in the endometriosis group and 100 (50%) in the hysterectomy group. The endometriosis group was characterized by younger age and lower parity (both, p<0.001). There was no significant difference between the groups in mean VAS scores for each post-operative day. However, among patients who needed additional analgesics beyond the standard protocol on POD 1, a higher percentage of women in the endometriosis group used opioids rather than milder analgesics, as compared to controls (1% vs. 0.2%, respectively, p = 0.03).

conclusionIncreased post-operative morphine use was observed in patients with endometriosis following laparoscopic surgery, despite no significant difference in mean VAS scores during the post-operative days. These findings suggest that personalized pain relief protocols should be adjusted for women with endometriosis.

Indexed as

EndometriosisHysterectomyLaparoscopyPostoperative PainAcetaminophenAdultAnalgesicsAnalgesics, OpioidFemaleHumansMiddle AgedMorphinePain MeasurementRetrospective StudiesAcetaminophenAnalgesicsAnalgesics, OpioidMorphine

Identifiers

PMID39365777
PMCPMC11452001

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.