Evidence map›Paper›PMID 39365671›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2024

Characterizing vascular and hormonal changes in women across the life span: a cross-sectional analysis.

Megan M Wenner, Ninette Shenouda, Leena Shoemaker, Andrew Kuczmarski, Katherine Haigh, Angelica Del Vecchio, Allyson Schwab, Shane J McGinty, David G Edwards, Ryan T Pohlig and 3 more

Abstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Sex comparison of cerebrovascular reactivity to COJournal of applied physiology (Bethesda, Md. : 1985) · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Sex differences in central salt sensing in the human brain.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Sex-specific effects of mild kidney dysfunction on vascular function in midlife and older adults.American journal of physiology. Heart and circulatory physiology · 2025
    Article
  18. ET(-1) phone home: a commentary on the complexities of cardiovascular disease risk in postmenopausal women.American journal of physiology. Heart and circulatory physiology · 2025
    Article
  19. The effect of transient sex hormone fluctuations on vascular endothelial function.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Megan M WennerDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.ORCID 0000-0003-0055-783X
Ninette ShenoudaDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.ORCID 0000-0001-6505-7057
Leena ShoemakerDepartment of Medical Biophysics, Western University, London, Ontario, Canada.
Andrew KuczmarskiDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.
Katherine HaighSchool of Nursing, University of Delaware, Newark, Delaware, United States.
Angelica Del VecchioDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.
Allyson SchwabDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.
Shane J McGintyDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.ORCID 0000-0002-1784-9815
David G EdwardsDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.ORCID 0000-0002-5098-6678
Ryan T PohligDepartment of Epidemiology, University of Delaware, Newark, Delaware, United States.
Virginia R NuckolsDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.ORCID 0000-0001-5879-5991
Lyndsey DuBoseDepartment of Medicine, Division of Geriatric Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.ORCID 0000-0002-3566-4531
Kerrie L MoreauDepartment of Medicine, Division of Geriatric Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.ORCID 0000-0001-9298-047X

Funding

Vascular Consequences of Duchenne Muscular DystrophyP20GM113125 · NIGMS · UNIVERSITY OF DELAWARE · PI LENNON, SHANNON L. · 2016 to 2025
$23.3M
Suppression of ERalpha in Hematopoietic Stem Cell-Derived Adipocytes Increases Adiposity via Kynurenine and the Aryl Hydrocarbon ReceptorU54AG062319 · NIA · UNIVERSITY OF COLORADO DENVER · PI Kerrie Moreau · 2018 to 2026
$13.5M
Mechanisms of Vascular Dysfunction with Advancing Reproductive AgeR01HL146558 · NHLBI · UNIVERSITY OF DELAWARE · PI WENNER, MEGAN M · 2019 to 2023
$2.3M
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01 HL 146558HHS | NIH | National Institute of General Medical Sciences (NIGMS) P20 GM 113125NHLBI NIH HHS R01 HL146558NIA NIH HHS U54 AG062319NIGMS NIH HHS P20 GM113125
6 · The paper itself

Abstract

Vascular dysfunction, marked by lower endothelial function and increased aortic stiffness, is a nontraditional risk factor that precedes the development of cardiovascular disease (CVD). However, the age at which these changes in vascular function occur in women and the degree to which reproductive hormones mediate these changes has not been characterized. Women free from major disease were enrolled across the adult life span (aged 18-70 yr,

Indexed as

Brachial ArteryEndothelium, VascularProgesteroneVascular StiffnessVasodilationAdolescentAdultAgedAge FactorsAgingCarotid-Femoral Pulse Wave VelocityCross-Sectional StudiesEstradiolFemaleFollicle Stimulating HormoneHumansEstradiolFollicle Stimulating HormoneProgesteroneagingarterial stiffnessendothelial functionestrogensex hormones

Identifiers

PMID39365671
PMCPMC11559635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.