Evidence map›Paper›PMID 39365639›Full record

ArticleJournal of the American Society for Mass Spectrometry2024

Enzymatic Synthesis of Isotopically Labeled Hydrogen Peroxide for Mass Spectrometry-Based Applications.

Margaret Hoare, Ruiyue Tan, Isabella Militi, Kevin A Welle, Kyle Swovick, Jennifer R Hryhorenko, Sina Ghaemmaghami

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Margaret HoareDepartment of Biology, University of Rochester, Rochester, New York 14627, United States.
Ruiyue TanDepartment of Biology, University of Rochester, Rochester, New York 14627, United States.
Isabella MilitiDepartment of Biology, University of Rochester, Rochester, New York 14627, United States.
Kevin A WelleUniversity of Rochester Mass Spectrometry Resource Laboratory, University of Rochester Medical Center, Rochester, New York 14627, United States.
Kyle SwovickUniversity of Rochester Mass Spectrometry Resource Laboratory, University of Rochester Medical Center, Rochester, New York 14627, United States.
Jennifer R HryhorenkoUniversity of Rochester Mass Spectrometry Resource Laboratory, University of Rochester Medical Center, Rochester, New York 14627, United States.
Sina GhaemmaghamiDepartment of Biology, University of Rochester, Rochester, New York 14627, United States.ORCID 0000-0002-8696-2950

Funding

The prevalence and mechanism of selectivity in basal autophagyR35GM119502 · NIGMS · UNIVERSITY OF ROCHESTER · PI SINA GHAEMMAGHAMI · 2016 to 2026
$5.9M
Orbitrap Fusion Lumos Mass Spectrometer for UR Proteomics ResearchS10OD025242 · OD · UNIVERSITY OF ROCHESTER · PI GHAEMMAGHAMI, SINA · 2018 to 2018
$1.1M
NIGMS NIH HHS R35 GM119502NIH HHS S10 OD025242
6 · The paper itself

Abstract

Methionine oxidation is involved in multiple biological processes including protein misfolding and enzyme regulation. However, it is often challenging to measure levels of methionine oxidation by mass spectrometry, in part due to the prevalence of artifactual oxidation that occurs during the sample preparation and ionization steps of typical proteomic workflows. Isotopically labeled hydrogen peroxide (H

Indexed as

Glucose OxidaseHydrogen PeroxideIsotope LabelingMass SpectrometryMethionineOxidation-ReductionOxygen IsotopesGlucoseGlucoseGlucose OxidaseHydrogen PeroxideMethionineOxygen IsotopesGlucose Oxidase (GOx)Mass Spectrometry (MS)Methionine Oxidation

Identifiers

PMID39365639
PMCPMC11622373

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.