Evidence map›Paper›PMID 39365517›Full record

ReviewCell biochemistry and biophysics2025

Olfactory Receptors and Tumorigenesis: Implications for Diagnosis and Targeted Therapy.

Yi Tang, Ye Tian, Chun-Xia Zhang, Guo-Tai Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cell biochemistry and biophysics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yi Tang *Shaanxi University of Chinese Medicine, Xianyang, China.
Ye Tian *Department of Oncology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, China.
Chun-Xia ZhangShaanxi University of Chinese Medicine, Xianyang, China.
Guo-Tai WangDepartment of Hepatobiliary Surgery, Affiliated Hospital of Shaanxi University of Chinese Medicine, Sub No.2, Weiyang West Road, Qindu District, Xianyang, 712000, China. guotaiwang52@sntcm.edu.cn.

Funding

Administration of Traditional Chinese Medicine of Shaanxi Province in China 2021-PY-002Department of Science and Technology of Shaanxi Province in China 2023-JC-QN-0865Education Department of Shaanxi Provincial Government in China 22JK0342Foundation of Shaanxi University of Traditional Chinese Medicine 2021GP02
6 · The paper itself

Abstract

Olfactory receptors (ORs) are a class of G protein-coupled receptors (GPCR) widely distributed in olfactory sensory neurons and various non-olfactory tissues, serving significant physiological and pathological functions in the human body. Increasing evidence reveals the heightened expression of olfactory receptors in tumorous tissues and cells alongside normal tissues. Olfactory receptors have demonstrated influence over tumor cell proliferation and metastasis, establishing a close relationship with tumor initiation and progression. This review highlights the specific molecular actions and signaling pathways of olfactory receptors in the development of human tumors. The potential for precise tumor diagnosis and targeted therapy through therapeutic targeting of olfactory receptors as an adjunct anticancer treatment strategy is being considered.

Indexed as

CarcinogenesisMolecular Targeted TherapyNeoplasmsReceptors, OdorantAnimalsHumansSignal TransductionReceptors, OdorantG Protein-coupled receptorsOlfactory receptorsTherapeutic targetingTumor cell proliferationTumor developmentTumor metastasis

Identifiers

PMID39365517

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.