Evidence map›Paper›PMID 39365429›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2024

Antibacterial and antibiofilm activity of human gut lactic acid bacteria.

Sherin Joy Parappilly, E K Radhakrishnan, Sumi Mary George

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sherin Joy ParappillyPost Graduate and Research Department of Microbiology, Sree Sankara College, Kalady, 683574, Kerala, India.
E K RadhakrishnanSchool of Biosciences, Mahatma Gandhi University, Kottayam, Kerala, India.
Sumi Mary GeorgePost Graduate and Research Department of Microbiology, Sree Sankara College, Kalady, 683574, Kerala, India. sumijimson@gmail.com.ORCID http://orcid.org/0000-0002-7732-560X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study focused on the antibacterial and antibiofilm activity of novel lactic acid bacterial (LAB) strains isolated from the healthy human volunteers of different age groups and their consortium (LABCON), against the enteropathogenic bacteria. From the study, methanolic extract of LAB isolates and their consortia were found to have promising antibacterial activity and antibiofilm activity against Escherichia coli (ATCC 35218) and Staphylococcus aureus (ATCC 25923). The antimicrobial compounds including the DL-3 phenyllactic acid, DL-p-hydroxyphenyllactic acid, and Succinic acid produced by the LAB could be considered to inhibit the growth and biofilm formation by E. coli (ATCC 35218) and S. aureus (ATCC 25923). Detailed insight into the antibiofilm activity could also be demonstrated by Confocal Raman microscopy attached with AFM and Fluorescent microscope. From the results of the study, the consortium LABCON was superior in antimicrobial and antibiofilm activity and can be considered to have promising application in infection control.

Indexed as

Anti-Bacterial AgentsBiofilmsGastrointestinal MicrobiomeLactobacillalesAdultEscherichia coliHumansMicrobial Sensitivity TestsStaphylococcus aureusAnti-Bacterial AgentsAFMAntibacterialAntibiofilmEnteropathogensFluorescent microscopeHuman gutLactic acid bacteria

Identifiers

PMID39365429
PMCPMC11711747

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.