Evidence map›Paper›PMID 39365403›Full record

ArticleJournal of medical ultrasonics (2001)2025

Blood flow signals through the bone cortex on ultrasonography can be used as a screening test for detecting bone marrow lesions on magnetic resonance imaging in patients with early knee osteoarthritis.

Naoki Takemoto, Yasushi Takata, Yosuke Shima, Kenichi Goshima, Kengo Shimozaki, Mitsuhiro Kimura, Tomoyuki Kanayama, Satoru Demura, Junsuke Nakase

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Article in Journal of medical ultrasonics (2001), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Naoki TakemotoDepartment of Orthopedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan. t.naoki7011@gmail.com.ORCID http://orcid.org/0000-0002-1518-1428
Yasushi TakataDepartment of Orthopedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan.
Yosuke ShimaDepartment of Orthopedic Surgery, KKR Hokuriku Hospital, Kanazawa, Ishikawa, 921-8035, Japan.
Kenichi GoshimaDepartment of Orthopedic Surgery and Joint Reconstructive Surgery, Kanazawa Munehiro Hospital, Kanazawa, Ishikawa, 920-0923, Japan.
Kengo ShimozakiDepartment of Orthopedic Surgery, Nomi Municipal Hospital, Nomi, Ishikawa, 929-0122, Japan.
Mitsuhiro KimuraDepartment of Orthopedic Surgery, Fukui General Hospital, Fukui, 910-3113, Japan.
Tomoyuki KanayamaDepartment of Orthopedic Surgery, KKR Hokuriku Hospital, Kanazawa, Ishikawa, 921-8035, Japan.
Satoru DemuraDepartment of Orthopedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan.
Junsuke NakaseDepartment of Orthopedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBlood flow signals (BFSs) through the bone cortex on ultrasonography (US) and bone marrow lesions (BMLs) detected on magnetic resonance imaging (MRI) can be used to assess bone lesions; however, no studies have reported their relationship. Therefore, this study aimed to assess whether BFSs through the bone cortex on US can serve as a screening test for detecting BMLs on MRI in patients with early knee osteoarthritis (OA).

methodsThis study enrolled patients with knee joint pain who were diagnosed with early knee OA between January 2018 and January 2024. We targeted 77 patients who underwent MRI and in whom the presence or absence of BFSs through the bone cortex was confirmed on US. The association between BFSs and BMLs was evaluated using the chi-square test, and the sensitivity and specificity of BFSs for detecting BMLs on MRI were calculated.

resultsThe chi-square test showed that BFSs and BMLs were significantly associated in the femur and tibia (femur: χ

conclusionBFSs through the bone cortex on US can be used as a screening test for detecting BMLs on MRI in patients with early knee OA.

Indexed as

Bone MarrowMagnetic Resonance ImagingOsteoarthritis, KneeAgedFemaleFemurHumansMaleMiddle AgedSensitivity and SpecificityTibiaUltrasonographyBlood flow signalsBone marrow lesionsMagnetic resonance imagingOsteoarthritisUltrasonography

Identifiers

PMID39365403

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