Evidence map›Paper›PMID 39365382›Full record

ArticleBiological trace element research2025

Investigation of the Effect of Omega-3 Fatty Acids on Antioxidant System and Serum Aluminum, Zinc, and Iron Levels in Acute Aluminum Toxicity.

Emine Atakisi, Onur Atakisi, Melek Ozturkler, Kezban Yildiz Dalginli, Cagatay Ozbey

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Article in Biological trace element research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Emine AtakisiDepartment of Biochemistry, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey. et_tasci@hotmail.com.
Onur AtakisiDepartments of Chemistry, Faculty of Science and Letter, Kafkas University, Kars, Turkey.
Melek OzturklerDepartment of Chemistry and Chemical Processing Technologies, Kars Vocational School, Kafkas University, Kars, Turkey.
Kezban Yildiz DalginliDepartment of Chemistry and Chemical Processing Technologies, Kars Vocational School, Kafkas University, Kars, Turkey.
Cagatay OzbeyDepartment of Medical Services and Techniques, Atatürk Vocational School of Health Services, Kafkas University, Kars, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aluminum (Al), one of the three most prevalent metals in the Earth's crust, adversely impacts all metabolic systems of living organisms due to its extensive utilization by humans. It is known that omega-3 fatty acids (ω-3FA) protect the organism against diseases and have positive effects on the immune system. The aim of the study was to investigate the effect of ω-3FA on 8-OH-2-deoxyguanosine (8-OHdG), glutathione (GSH) levels and adenosine deaminase (ADA), paraoxonase (PON), and catalase (CAT) activities in rats with acute aluminum toxicity. The study also aimed to investigate the antioxidant system, as well as Al, zinc (Zn), and iron (Fe) levels. Forty Sprague-Dawley rats (n = 40) were used in the study and the rats were divided into four equal groups (n = 10). In group I, 0.5 mL of 0.9% saline solution (NaCI) was injected intraperitoneally. Group II was injected with 34 mg/kg aluminum chloride (AlCI

Indexed as

AluminumAntioxidantsFatty Acids, Omega-3IronZincAnimalsMaleOxidative StressRatsRats, Sprague-DawleyAluminumAntioxidantsFatty Acids, Omega-3IronZincAluminumHeavy metalsOmega-3 fatty acidsRatToxicity

Identifiers

PMID39365382

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.