Evidence map›Paper›PMID 39365369›Full record

ArticleTechniques in coloproctology2024

Temporal trends and treatment patterns in anal fissure management: insights from a multicenter study in Italy.

A Picciariello, R Tutino, G Gallo, D F Altomare, R Pietroletti, A Dezi, G Graziano, SICCR Anal Fissure Group, U Grossi

Abstract readMulticenter Study
In one paragraph

Article in Techniques in coloproctology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

A PicciarielloDepartment of Experimental Medicine, University of Salento, Lecce, Italy.
R TutinoDepartment of General and Emergency Surgery, AOU Città della Salute e della Scienza, Turin, Italy.
G GalloDepartment of Surgery, Sapienza University of Rome, Rome, Italy. ga.gallo@uniroma1.it.
D F AltomareDepartment of Precision and Regenerative Medicine and Ionian Area and Interdepartmental Research Center for Pelvic Floor Diseases (CIRPAP), University Aldo Moro of Bari, Bari, Italy.
R PietrolettiDepartment of Biotechnological and Applied Clinical Sciences, Proctology Unit, University of L'Aquila, L'Aquila, Italy.
A DeziDepartment of Precision and Regenerative Medicine and Ionian Area and Interdepartmental Research Center for Pelvic Floor Diseases (CIRPAP), University Aldo Moro of Bari, Bari, Italy.
G GrazianoCenter for Outcomes Research and Clinical Epidemiology (CORESEARCH), Pescara, Italy.
SICCR Anal Fissure Group
U GrossiOncology and Gastroenterology - DiSCOG, University of Padova, Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAnal fissure (AF) poses a common challenge in clinical practice, prompting various treatment approaches. This multicenter study, conducted by the Italian Society of Colorectal Surgery, aimed to assess treatment trends in AF over a 10 year period.

methodsA survey of proctologists and retrospective analysis of patient records were conducted to evaluate treatment modalities and outcomes across six different clinical scenarios based on AF presentation (acute/chronic) stratified by sphincter function (normal/hypertonic/hypotonic).

resultsAnalysis of data from 17 principal investigators and 22,016 patients revealed significant variability in treatment approaches, influenced by factors such as symptom duration, anal tone, and surgeon preference. Conservative treatments were commonly utilized, while surgical interventions were reserved for refractory cases. Specifically, pharmaceutical treatment was administered to 66-75% of patients in cases of acute AF and 63-67% for chronic AF, while 10-15% underwent anal dilation, and < 2% received botulinum toxin injection. Among medical treatments, nifedipine with lidocaine and glycerin film-forming ointments were the most utilized. The most performed surgical techniques were fissurectomy and anoplasty, except for patients with chronic AF and hypertonic sphincter where sphincterotomy prevailed. Trends in treatment utilization varied depending on the clinical scenario, with notable shifts observed over time.

conclusionsThis study provides insights into the evolving landscape of AF management, highlighting the need for further research to elucidate optimal treatment strategies and improve patient outcomes.

Indexed as

Fissure in AnoAcute DiseaseAdultAnal CanalChronic DiseaseConservative TreatmentDilatationFemaleHumansItalyLidocaineMaleMiddle AgedNifedipineNitroglycerinPractice Patterns, Physicians'LidocaineNifedipineNitroglycerinAnal fissureBotulinum toxin injectionConservative treatmentFissurectomySphincterotomySurgeryTrends

Identifiers

PMID39365369
PMCPMC11452494

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.