ArticleeLife2024
Inhibition of
Abstract read
In one paragraph
Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- O-GlcNAcylation: the metabolic-immune translator in tumor evolution and treatment.Molecular medicine (Cambridge, Mass.) · 2026Review
- Glycosylation as a dynamic regulator of RLR and cGAS-STING innate immune signalling pathways.Communications biology · 2026Review
- Dendritic cells in cancer immunotherapy: functional barriers, reprogramming strategies and translational challenges.Frontiers in immunology · 2026Review
- O-GlcNAcylation at the tumor-immune interface: a metabolic post-translational code driving immune evasion and therapy resistance in cancer.Frontiers in immunology · 2026Review
- Regulation of glycosylation in radiotherapy: exploring the multiple effects of DNA damage, immune response, stromal microenvironment and metabolism.Frontiers in oncology · 2026Review
- Review
- O‑GlcNAcylation as an emerging molecular target for cholangiocarcinoma therapy (Review).Oncology reports · 2025Review
- Crosstalk between O-GlcNAcylation and phosphorylation in metabolism: regulation and mechanism.Cell death and differentiation · 2025Review
- FBXO31-mediated ubiquitination of OGT maintains O-GlcNAcylation homeostasis to restrain endometrial malignancy.Nature communications · 2025Article
- Degradation of PARP1 by MARCHF3 in tumor cells triggers cCAS-STING activation in dendritic cells to regulate antitumor immunity in hepatocellular carcinoma.Journal for immunotherapy of cancer · 2024Article
- Inhibition ofeLife · 2024Article
- CanPharmaceuticals (Basel, Switzerland) · 2024Review
- Retinoid X receptor heterodimers in hepatic function: structural insights and therapeutic potential.Frontiers in pharmacology · 2024Review
Corrections and comments
- Update ofInhibition of2024
Authors and funding
14 authors.
Jianwen Chen *Department of Microbial Infection and Immunity, Infectious Disease Institute, The Ohio State University, Columbus, United States.
Bao Zhao *Department of Microbial Infection and Immunity, Infectious Disease Institute, The Ohio State University, Columbus, United States.
Hong Dong *Department of Microbial Infection and Immunity, Infectious Disease Institute, The Ohio State University, Columbus, United States.ORCID https://orcid.org/0000-0001-6719-4880
Tianliang LiDepartment of Microbial Infection and Immunity, Infectious Disease Institute, The Ohio State University, Columbus, United States.
Xiang ChengDepartment of Microbial Infection and Immunity, Infectious Disease Institute, The Ohio State University, Columbus, United States.
Wang GongDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, University of Michigan Rogel Cancer Center, University of Michigan, Ann Arbor, United States.
Jing WangPelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, United States.
Junran ZhangPelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, United States.
Gang XinDepartment of Microbial Infection and Immunity, Infectious Disease Institute, The Ohio State University, Columbus, United States.
Yanbao YuDepartment of Chemistry and Biochemistry, University of Delaware, Newark, United States.
Yu L LeiDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, University of Michigan Rogel Cancer Center, University of Michigan, Ann Arbor, United States.
Jennifer D BlackEppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, United States.
Zihai LiPelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, United States.
Haitao WenDepartment of Microbial Infection and Immunity, Infectious Disease Institute, The Ohio State University, Columbus, United States.ORCID https://orcid.org/0000-0002-6363-2748
Funding
Restoring the Immunogenicity of Head and Neck CancerR01DE026728 · NIDCR · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Yu Leo Lei, James J. Moon · 2018 to 2026
$4.3MMolecular chaperones and immune toleranceR01AI077283 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LI, ZIHAI · 2009 to 2021
$3.7MTargeting immune inhibitory molecule SUSD2 to reverse immunosuppressionR01AI162779 · NIAID · OHIO STATE UNIVERSITY · PI WEN, HAITAO · 2021 to 2025
$2.3MMitochondrial metabolism in microbial sepsisR01GM135234 · NIGMS · OHIO STATE UNIVERSITY · PI WEN, HAITAO · 2019 to 2022
$1.2MNIAID NIH HHS R01 AI077283NIAID NIH HHS R01 AI162779NIDCR NIH HHS R01 DE026728NIGMS NIH HHS R01 GM135234NIH HHS R01AI077283NIH HHS R01AI162779NIH HHS R01CA262089NIH HHS R01DE026728NIH HHS R01GM135234The Ohio State University Comprehensive Cancer Center Intramural Research Program
Abstract
The
Indexed as
Interferon Type IMembrane ProteinsN-AcetylglucosaminyltransferasesNucleotidyltransferasesAnimalsColorectal NeoplasmsCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseDisease Models, AnimalHumansMiceMice, Inbred C57BLMice, KnockoutSignal TransductionSTING ProteincGAS protein, mouseCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseInterferon Type IMembrane ProteinsN-AcetylglucosaminyltransferasesNucleotidyltransferasesO-GlcNAc transferaseSting1 protein, mouseSTING Proteincancer biologycGAScolorectal cancerimmunologyinflammationmouseOGTSTINGtumor immunity
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.