ArticleJournal of occupational health2024
Urinary benzyl alcohol and hippuric acid in workers exposed to benzyl alcohol during paint-stripping work.
Article in Journal of occupational health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Evaluation of synergistic factors on BTEX urinary biomarkers in motorcycle riders exposed to heavy traffic in a megacity.Scientific reports · 2025Article
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Authors and funding
12 authors.
Funding
Abstract
objectiveWe aimed to develop a reliable gas chromatography-mass spectrometry (GC-MS) method for detecting urinary benzyl alcohol (BeOH) concentrations and assess the suitability of urinary BeOH as a biomarker for occupational BeOH exposure.
methodsThirteen male participants exposed to BeOH during paint-stripping work provided preshift and postshift urine samples, and their personal exposure concentrations were measured. Meanwhile, a control group of 10 nonexposed workers contributed urine samples. The newly developed GC-MS method met regulatory guidelines.
resultsThe personal exposure concentrations of BeOH ranged from 8.4 to 45.2 mg/m3. Postshift urine samples from exposed participants showed significant BeOH and hippuric acid (HA) concentration increases compared with preshift samples (BeOH, post-/pre-shift geometric mean [GM] ratio = 7.5-7.8, P < .001; HA, post-/pre-shift GM ratio = 4.3-4.5, P < .001). These levels were considerably higher than those in postshift samples from the nonexposed control group (BeOH, exposed-/nonexposed-workers GM ratio = 14.8-19.0, P < .001; HA, exposed-/nonexposed-workers GM ratio = 12.1-15.3, P < .001), even after urine density correction.
conclusionsUrinary BeOH and HA can serve as potential biomarkers of occupational exposure to BeOH. More specifically, BeOH might serve as a biomarker superior to HA because it is apparently less influenced by confounding factors such as dietary intake and genetic polymorphism of low-Km aldehyde dehydrogenase (ALDH2). The findings will improve workplace safety measures and protocols, assisting health care professionals in diagnosing and managing exposure-related health issues, thereby potentially reducing the risk of occupational exposure to BeOH.
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Registered trials
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