Evidence map›Paper›PMID 39364678›Full record

ArticleACS biomaterials science & engineering2024

Shape Memory Polymer Bioglass Composite Scaffolds Designed to Heal Complex Bone Defects.

Brandon M Nitschke, Elizabeth A Butchko, MaryGrace N Wahby, Kaylee M Breining, Alexander E Konz, Melissa A Grunlan

Abstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brandon M NitschkeDepartment of Biomedical Engineering, Texas A&M University, College Station, Texas 77843, United States.
Elizabeth A ButchkoDepartment of Biomedical Engineering, Texas A&M University, College Station, Texas 77843, United States.
MaryGrace N WahbyDepartment of Biomedical Engineering, Texas A&M University, College Station, Texas 77843, United States.
Kaylee M BreiningDepartment of Materials Science and Engineering, Texas A&M University, College Station, Texas 77843, United States.
Alexander E KonzDepartment of Biomedical Engineering, Texas A&M University, College Station, Texas 77843, United States.
Melissa A GrunlanDepartment of Biomedical Engineering, Texas A&M University, College Station, Texas 77843, United States.ORCID 0000-0002-5428-0461

Funding

Synthetic Cartilage-Capped, Regenerative Osteochondral Plugs to Heal Osteochondral DefectsR01AR082652 · NIAMS · TEXAS ENGINEERING EXPERIMENT STATION · PI Melissa Grunlan · 2024 to 2026
$2.0M
NIAMS NIH HHS R01 AR082652
6 · The paper itself

Abstract

An off-the-shelf scaffold with requisite properties could enable the viable treatment of irregular craniomaxillofacial bone defects. Notably, the scaffold should be conformally fitting, innately bioactive, and bioresorbable. In prior work, we developed a series of shape memory polymer (SMP) scaffolds based on cross-linked poly(ε-caprolactone) (PCL). These were capable of "self-fitting" into complex bone defects when exposed to temperatures above the melt transition of the constituent PCL, either

Indexed as

CeramicsPolyestersTissue ScaffoldsAnimalsBiocompatible MaterialsBone and BonesBone RegenerationHumansMaterials TestingPolymersSmart MaterialsTissue EngineeringBiocompatible MaterialsBioglasspolycaprolactonePolyesterspoly(lactide)PolymersSmart Materialsbioactivitybioceramicbioglassbone regenerationcompositepolymerscaffold

Identifiers

PMID39364678
PMCPMC11480937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.