ArticleActa paediatrica (Oslo, Norway : 1992)2025
Providing very low-birth-weight infants with fast enteral feeding reduced how long they needed a central venous catheter.
Article in Acta paediatrica (Oslo, Norway : 1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Neonatal Intensive Care Admissions and Outcomes in Malta from 2019 to 2022-A Retrospective Observational Study.Children (Basel, Switzerland) · 2026Article
- Enteral feeding practices and guideline adherence for very low birth weight infants in Chinese NICUs: a multicentre cross-sectional survey.Frontiers in nutrition · 2026Article
- Risk factors of necrotizing enterocolitis in very low birth weight infants: a meta-analysis.Frontiers in pediatrics · 2026Review
- Time to Full Enteral Feeds and Late-Onset Sepsis in Extremely Preterm Infants.JAMA network open · 2025Article
- Providing very low-birth-weight infants with fast enteral feeding reduced how long they needed a central venous catheter.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
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Authors and funding
5 authors.
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Abstract
aimTo determine the impact of the protocol change from slow to fast enteral feeding progression on duration of central venous catheter placement, and the rates of late-onset sepsis and necrotising enterocolitis.
methodsWe compared the evolution of all very low-birth-weight infants admitted on their first postnatal day in neonatal intensive care unit during a 12-month period, before (2021 Cohort) and after (2022 Cohort) implementation of a new feeding protocol. Linear regression model was used to adjust for confounding factors.
resultsA total of 343 VLBW infants were included (median gestational age ± SD 28.3 ± 1.7 weeks; median birth weight ± SD 980 ± 300 g). Median initial duration of central venous catheter was 5 days in 2022 cohort compared with 9 days in 2021 cohort (unadjusted p = 0.006, adjusted p = 0.001). Median time to achieve full enteral feeding was 8 days versus 12 days, p < 0.001, with no significant difference in late-onset sepsis or necrotising enterocolitis rates.
conclusionThe change from slow to fast enteral feeding progression for very low-birth-weight infants significantly decreased the central venous catheter duration with no adverse outcomes. This is consistent with recent randomised study results and supports the safe implementation in neonatal intensive care units.
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