Evidence map›Paper›PMID 39364488›Full record

ArticleCureus2024

Leptomeningeal Carcinomatosis in a Young Patient With Colorectal Cancer: A Case Report.

Zamanali Khakhar, Soraiya Manji, Rajiv Patel, Karishma Sharma, Sheila Waa, Sayed K Ali

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zamanali KhakharDepartment of Medicine, University of Nairobi, Nairobi, KEN.
Soraiya ManjiDepartment of Internal Medicine, Aga Khan University Hospital, Nairobi, KEN.
Rajiv PatelDepartment of Internal Medicine, Aga Khan University Hospital, Nairobi, KEN.
Karishma SharmaDepartment of Internal Medicine, Aga Khan University Hospital, Nairobi, KEN.
Sheila WaaDepartment of Radiology, Aga Khan University Hospital, Nairobi, KEN.
Sayed K AliDepartment of Internal Medicine, Aga Khan University Hospital, Nairobi, KEN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leptomeningeal carcinomatosis (LMC) is a rare and fatal complication associated with various solid tumors and hematological malignancies. It presents significant diagnostic challenges due to its nonspecific symptoms and complex clinical course. This case report details the presentation, diagnosis, and implications of LMC in a 33-year-old male with a history of colorectal cancer (CRC) and hemicolectomy. The patient presented with nonspecific symptoms of headache and dizziness. Cerebrospinal fluid cytology revealed the presence of malignant cells, leading to the diagnosis of LMC secondary to CRC. The elusive and multifaceted nature of this condition highlights the necessity for increased clinical awareness and extensive research to improve the understanding and management of LMC.

Indexed as

carcinomatous meningitiscolon cancercolorectal cancer (crc)leptomeningeal carcinomatosis (lmc)neoplastic meningitis

Identifiers

PMID39364488
PMCPMC11448006

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.