Evidence map›Paper›PMID 39364391›Full record

ArticleCHEST critical care2024

Variation in Triage to Pediatric vs Adult ICUs Among Adolescents and Young Adults With Asthma Exacerbations.

Burton H Shen, Aaron C Dobie, Sara L Shusterman, Mine Duzgol, Collin Homer-Bouthiette, Lauren E Kearney, Julia Newman, Brandon Pang, Divya A Shankar, Jingzhou Zhang and 3 more

Abstract read
In one paragraph

Article in CHEST critical care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Burton H ShenPulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Aaron C DobiePulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Sara L ShustermanPulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Mine DuzgolPediatric Infectious Disease, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Collin Homer-BouthiettePulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Lauren E KearneyPulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Julia NewmanPulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Brandon PangPulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Divya A ShankarPulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Jingzhou ZhangPulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Kari R GillmeyerPulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Nicholas A BoschPulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Anica C LawPulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.

Funding

Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
BIOLOGY OF THE LUNG--MULTIDISCIPLINARY PROGRAMT32HL007035 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Darrell N. Kotton, JOSEPH P MIZGERD · 1985 to 2026
$24.3M
Institutional Career DevelopmentKL2TR001411 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MORONE, NATALIA E. · 2015 to 2024
$5.9M
Prolonged mechanical ventilation: patterns of post-acute care and patient outcomesK23HL153482 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LAW, ANICA C · 2020 to 2024
$891k
Veteran-Centered Transformation of Pulmonary Hypertension Organization into a Regional Model of Care in VA (TRANSPHORM-VA)IK2HX003700 · VA · VA BOSTON HEALTH CARE SYSTEM · PI Kari Gillmeyer · 2024 to 2026
–
HSRD VA IK2 HX003700NCATS NIH HHS KL2 TR001411NCATS NIH HHS UL1 TR001430NHLBI NIH HHS K23 HL153482NHLBI NIH HHS T32 HL007035
6 · The paper itself

Abstract

backgroundMore than 90,000 children and adults in the United States are hospitalized with an asthma exacerbation annually, and between 5% and 34% of these hospitalizations include admission to an ICU. It is unclear how adolescent and young adults with severe asthma exacerbations are triaged in the inpatient setting between PICUs and adult ICUs. Using a large multicenter US cohort, we characterized how hospitals triage adolescents and young adults with asthma exacerbations between PICUs and adult ICUs. RESEARCH QUESTION: How do hospitals across the United States triage adolescents and young adults with asthma exacerbations between PICUs and adult ICUs? STUDY DESIGN AND

methodsThis was a retrospective cohort study carried out from 2016 through 2022 using the enhanced-claims PINC AI database. Participants were patients aged 12 to 26 years who were hospitalized with an asthma exacerbation and admitted to a PICU or adult ICU. We used nested hierarchical multivariable regression models to quantify changes in the intraclass correlation coefficient (ICC; a measure of variation in triage decisions attributable to hospital of admission after accounting for covariables).

resultsAnalyses included 3,946 admissions from 93 hospitals. Stratified by age, the percent of patients admitted to PICUs dropped by 26.9% between 17 and 18 years of age. In the nested models, the ICC showed a large decrease going from the empty model (28.7%) to the age-adjusted model (4.5%), but was similar between the age-adjusted and fully adjusted model (3.4%).

interpretationOur results showed that among adolescents and young adults with asthma exacerbations, age of 18 years or younger was a strong determinant of PICU triage. Further research is needed to understand differences in asthma care and outcomes between PICUs and adult ICUs, as well as how intermediate care units affect triage decision-making from wards and the ED.

Indexed as

asthmaMICUPICUpractice variation

Identifiers

PMID39364391
PMCPMC11449464

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.