ArticleEuropean heart journal. Case reports2024
Pannus formation: a rare culprit of early bioprosthetic valve dysfunction-a case report.
Article in European heart journal. Case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- A predictive model for differentiating causes of elevated mechanical prosthetic aortic valve gradient.The international journal of cardiovascular imaging · 2025Article
- Early TAVR Explantation Due to a Large Mobile Leaflet Mass and Severe Prosthetic Valve Stenosis.JACC. Case reports · 2025Article
- Stuck Prosthetic Valves: Clinical Implications of Pannus Formation and Gradient Measurement in Surgical Outcomes.Journal of clinical medicine · 2025Article
- Severe Mitral Stenosis and Regurgitation Due to Bioprosthetic Valve Failure with Massive Pannus.Surgical case reports · 2025Article
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Authors and funding
4 authors.
Funding
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Abstract
Background: Early bioprosthetic valve dysfunction (BVD) due to pannus formation is uncommon in elderly patients, and only a limited number of cases have been reported. Case summary: An 84-year-old man presented with exertional dyspnoea 3 years after surgical aortic valve replacement (SAVR) with a 19 mm Epic™ valve (Abbott, Santa Clara, CA, USA). Transthoracic echocardiography demonstrated progressive BVD, and cardiac computed tomography (CT) revealed sub-aortic pannus formation. Re-operative SAVR was performed using a 19 mm INSPIRIS RESILIA® valve (Edwards Lifesciences, Irvine, CA, USA), and pathological examination confirmed valve leaflet deformation caused by pannus overgrowth. At the 18-month follow-up, the patient exhibited favourable progress, with no indications of BVD or pannus recurrence. Discussion: This case highlights the importance of recognizing early pannus formation as a cause of BVD, even in elderly patients. Early detection of BVD based on clinical symptoms and echocardiography is vital to allow timely surgical intervention before the deterioration of cardiac function. Cardiac CT helps to differentiate pannus from thrombus formation and guide treatment decisions.
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