Evidence map›Paper›PMID 39364338›Full record

ArticleWellcome open research2023

VIVALDI Cohort Profile: Using linked, routinely collected data and longitudinal blood sampling to characterise COVID-19 infections, vaccinations, and related outcomes in care home staff and residents in England.

Maria Krutikov, David Bone, Oliver Stirrup, Rachel Bruton, Borscha Azmi, Chris Fuller, May Lau, Juliet Low, Shivika Rastogi, Igor Monakhov and 6 more

Abstract read
In one paragraph

Article in Wellcome open research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Maria KrutikovInstitute of Health Informatics, University College London, London, England, NW1 2DA, UK.ORCID https://orcid.org/0000-0002-3982-642X
David BoneInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, England, B15 2TT, UK.
Oliver StirrupInstitute for Global Health, University College London, London, England, WC1N 1EH, UK.ORCID https://orcid.org/0000-0002-8705-3281
Rachel BrutonInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, England, B15 2TT, UK.
Borscha AzmiInstitute of Health Informatics, University College London, London, England, NW1 2DA, UK.
Chris FullerInstitute of Health Informatics, University College London, London, England, NW1 2DA, UK.
May LauInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, England, B15 2TT, UK.
Juliet LowInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, England, B15 2TT, UK.
Shivika RastogiInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, England, B15 2TT, UK.
Igor MonakhovUK Health Security Agency, London, SW1P 3JR, UK.
Gokhan TutInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, England, B15 2TT, UK.
Douglas FinkDivision of Infection & Immunity, University College London, London, England, WC1E 6JF, UK.
Paul MossInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, England, B15 2TT, UK.ORCID https://orcid.org/0000-0002-6895-1967
Andrew HaywardInstitute of Epidemiology & Health Care, University College London, London, England, WC1E 7HB, UK.ORCID https://orcid.org/0000-0002-3549-6232
Andrew CopasInstitute for Global Health, University College London, London, England, WC1N 1EH, UK.
Laura ShallcrossInstitute of Health Informatics, University College London, London, England, NW1 2DA, UK.ORCID https://orcid.org/0000-0003-1713-2555

Funding

Wellcome Trust
6 · The paper itself

Abstract

VIVALDI (ISRCTN14447421) is a government-funded longitudinal open observational cohort study of staff and residents in care homes for older people in England. The study aimed to describe epidemiology (including seroprevalence) and immune responses to COVID-19 in a subset of care homes, in the context of extremely high mortality in this setting, in the first 12-18 months of the pandemic. Data linkage to routine health data was undertaken for all staff and residents and a subset of individuals who consented to sequential blood sampling to investigate SARS-CoV-2 immunity. This paper aims to describe the samples stored within the VIVALDI biobank and associated linked data, available for use by researchers. Over 70,000 individuals from 346 care homes were included in the data linkage cohort (1

Indexed as

care homesCOVID-19data linkageinfectionolder adults

Identifiers

PMID39364338
PMCPMC11447437

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.