Evidence map›Paper›PMID 39364331›Full record

ArticleSouthern African journal of infectious diseases2024

Viral load non-suppression among adolescents and youth living with HIV in South Africa.

Lesiba O Molopa, Thembelihle P Ginyana, Noloyiso Vondo, Rindidzani Magobo, Goitseone Maseko, Nompumelelo Zungu, Khangelani Zuma, Leickness Simbayi, Musawenkosi Mabaso, Sizulu Moyo

Abstract read
In one paragraph

Article in Southern African journal of infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lesiba O MolopaDivision of Public Health Societies and Belonging, Human Sciences Research Council, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-4893-9378
Thembelihle P GinyanaDivision of Public Health Societies and Belonging, Human Sciences Research Council, Cape Town, South Africa.ORCID https://orcid.org/0009-0005-5660-3569
Noloyiso VondoDivision of Public Health Societies and Belonging, Human Sciences Research Council, Cape Town, South Africa.ORCID https://orcid.org/0000-0001-5996-5171
Rindidzani MagoboDivision of Public Health Societies and Belonging, Human Sciences Research Council, Pretoria, South Africa.ORCID https://orcid.org/0000-0002-0950-0146
Goitseone MasekoDivision of Public Health Societies and Belonging, Human Sciences Research Council, Pretoria, South Africa.ORCID https://orcid.org/0009-0000-6172-6452
Nompumelelo ZunguDivision of Public Health Societies and Belonging, Human Sciences Research Council, Pretoria, South Africa.ORCID https://orcid.org/0000-0003-1275-2317
Khangelani ZumaDivision of Public Health Societies and Belonging, Human Sciences Research Council, Pretoria, South Africa.ORCID https://orcid.org/0000-0003-4492-5083
Leickness SimbayiDivision of Public Health Societies and Belonging, Human Sciences Research Council, Cape Town, South Africa.ORCID https://orcid.org/0000-0001-6136-4092
Musawenkosi MabasoDivision of Public Health Societies and Belonging, Human Sciences Research Council, Durban, South Africa.ORCID https://orcid.org/0000-0002-9475-2048
Sizulu MoyoDivision of Public Health Societies and Belonging, Human Sciences Research Council, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-5296-3242

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Despite the increased initiation and uptake of antiretroviral therapy (ART) in South Africa, some people living with HIV (PLHIV) who are on ART still have non-suppressed viral load (VL). Objectives: This study aimed to determine the prevalence of VL non-suppression among adolescents and youth (aged 12 years - 24 years) living with HIV and on ART in South Africa, as well as the factors associated with it. Method: Data from the 2017 South African national HIV prevalence, incidence, behaviour, and communication survey were analysed. The survey used a multistage-stratified cluster sampling design. A backward stepwise multivariable generalised linear model was used to identify factors associated with VL non-suppression. Results: The study included 340 participants aged 12 years - 24 years, with a median age of 21 (interquartile range [IQR]: 18-23). The proportion of adolescents and youth living with HIV and on ART with non-suppressed VL was 19.2% (95% confidence interval [CI]: 14.4-25.3). Approximately 60% of the participants were not on ART. The odds of VL non-suppression were significantly higher among youth aged 15 years - 19 years (adjusted odds ratio [AOR] = 1.63 [95% CI: 1.24-2.13], Conclusion: Findings suggest a need for ART education and counselling as part of treatment support. In addition, the promotion of HIV awareness as part of strengthening the HIV treatment and prevention cascade. Contribution: The article showed the prevalence of VL non-suppression and associated factors among adolescents and youth.

Indexed as

adolescentantiretroviral treatmentHIVnon-suppressionSouth Africaviral loadyouth

Identifiers

PMID39364331
PMCPMC11447573

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.