ArticleFrontiers in oncology2024
Association between smoking status and the prognosis of brain metastasis in patients with non-small cell lung cancer.
Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aimed to explore the relationship between smoking status and the interval to brain metastasis in patients with non-small cell lung cancer (NSCLC) and its impact on survival time after brain metastasis. Methods: Data were collected from patients with NSCLC with brain metastases who were treated at our centre between January 2005 and December 2017. Clinical indices such as clinicopathological features and smoking status were recorded, and patients were followed up until 1 September 2022. Based on our inclusion and exclusion criteria, 461 patients were analysed and matched using 1:1 propensity score matching. Three balanced groups were formed: non-smoking (n = 113), smoking cessation (n = 113), and smoking (n = 113). The interval to brain metastasis and overall survival were compared between the groups. Results: There was a statistically significant difference in the interval to brain metastasis between the non-smoking and smoking cessation groups ( Conclusion: Smoking status in patients with NSCLC affects the interval to brain metastasis and survival after brain metastasis.
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