ArticleFrontiers in medicine2024
Elevated serum albumin-to-creatinine ratio as a protective factor on clinical outcomes among critically ill patients with sepsis: a retrospective study.
Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Article
- The creatinine-to-albumin ratio as a prognostic indicator in critically ill patients with cirrhosis: A cohort study.Medicine · 2026Article
- Predictive value of the albumin-to-creatinine and bicarbonate-to-lactate ratios for 28-day mortality in acute mesenteric ischemia.Turkish journal of surgery · 2026Article
- Albumin-Anchored Composite Ratios of Blood Urea Nitrogen, C-Reactive Protein, Lactate, and Creatinine for Predicting Mortality in Chronically Ill Intensive Care Unit Patients.Journal of clinical medicine · 2026Article
- Trajectory of early creatinine change is associated with the prognosis of sepsis patients.BMC infectious diseases · 2026Article
- Article
- Trajectory models of serum creatinine and 28-day mortality in critically ill patients with sepsis complicated by type 2 diabetes mellitus: a cohort study.Frontiers in endocrinology · 2026Article
- Association of serum high creatinine-to-albumin ratio with increased 1-year mortality in older patients following hip fracture surgery.Frontiers in medicine · 2026Article
- A single-center study on epidemiology, microbial distribution, and mortality predictors in catheter-related bloodstream infections.BMC infectious diseases · 2025Article
- Association between the serum albumin-to-creatinine ratio and prognosis and risk of severe disturbance of consciousness in intracerebral hemorrhage patients.Scientific reports · 2025Article
- Association of serum albumin to creatinine ratio with mortality in patients with aortic disease: a cohort study.Scientific reports · 2025Article
- Association of serum creatinine-to-albumin ratio with 28-day all-cause mortality in older adults critically ill patients with sepsis: a retrospective analysis of the MIMIC-IV database.BMC geriatrics · 2025Article
- Association of Inflammatory and Metabolic Markers with Mortality in Patients with Postoperative Femur Fractures in the Intensive Care Unit.Medicina (Kaunas, Lithuania) · 2025Article
- Association between the serum albumin-to-creatinine ratio and 28-day all-cause mortality in sepsis: a retrospective cohort study.Frontiers in medicine · 2025Article
- The non-linear association between creatinine-to-albumin ratio and medium-term mortality in patients with sepsis accompanied by acute kidney injury in the intensive care unit: a retrospective study based on the MIMIC database and external validation.Frontiers in cellular and infection microbiology · 2025Article
- Association between creatinine-to-albumin ratio and mortality in intracerebral hemorrhage: a superior predictive indicator.Frontiers in neurology · 2025Article
- Correlation Between Serum Creatinine-to-Cystatin C Ratio and Prognosis of Patients with Hip Fracture.International journal of general medicine · 2025Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: The aim of this study was to examine the prognostic significance of serum albumin-to-creatinine ratio (ACR) in critically ill patients with sepsis. Methods: This retrospective study analyzed sepsis cases admitted to the Affiliated Hospital of Jiangsu University between January 2015 and November 2023. The patients were divided into four groups based on their ACR upon admission to the intensive care unit (ICU). Laboratory data were collected at the time of ICU admission, and the primary outcome measure was in-hospital all-cause mortality. Kaplan-Meier survival curves were generated to illustrate the differences in 30-/60-day mortality among the various groups. Multivariate Cox regression models and restricted cubic splines (RCS) were utilized to explore the association between ACR and all-cause mortality in sepsis patients. Subgroup analyses were conducted to examine the impact of other covariates on the relationship between ACR and all-cause mortality. Results: A total of 1,123 eligible patients were included in the study, with a median ACR of 0.169. The in-hospital mortality rate was 33.7%, the ICU mortality rate was 31.9%, and the 30-day mortality rate was 28.1%. Kaplan-Meier survival analysis demonstrated that patients with higher ACR had a significantly lower risk of 30-/60-day mortality (log-rank Conclusion: Low ACR levels were identified as independent risk factors associated with increased in-hospital, ICU, and 30-day mortality in sepsis patients. ACR can serve as a significant predictor of the clinical outcome of sepsis.
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