Evidence map›Paper›PMID 39364002›Full record

ArticleComputing in cardiology2023

Prediction of Hypoxic-Ischemic Encephalopathy Using Events in Fetal Heart Rate and Uterine Pressure.

Johann Vargas-Calixto, Yvonne W Wu, Michael Kuzniewicz, Marie-Coralie Cornet, Heather Forquer, Lawrence Gerstley, Emily Hamilton, Philip Warrick, Robert Kearney

Abstract read
In one paragraph

Article in Computing in cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Accounting for Nulliparity in the Prediction of Hypoxic-Ischemic Encephalopathy Using Cardiotocography.... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Johann Vargas-CalixtoMcGill University, Montreal, Canada.
Yvonne W WuUniversity of California, San Francisco, USA.
Michael KuzniewiczKaiser Permanente, Oakland, USA.
Marie-Coralie CornetUniversity of California, San Francisco, USA.
Heather ForquerKaiser Permanente, Oakland, USA.
Lawrence GerstleyKaiser Permanente, Oakland, USA.
Emily HamiltonMcGill University, Montreal, Canada.
Philip WarrickMcGill University, Montreal, Canada.
Robert KearneyMcGill University, Montreal, Canada.

Funding

Maternal Antecedents and Electronic Fetal Monitoring in Term Asphyxia (MAESTRA)R01HD099216 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KEARNEY, ROBERT EDWARD, WU, YVONNE W · 2020 to 2025
$2.8M
NICHD NIH HHS R01 HD099216
6 · The paper itself

Abstract

The objective of this work was to evaluate the utility of using intrapartum fetal heart rate (FHR) and uterine pressure (UP) events to detect infants at risk of hypoxic-ischemic encephalopathy (HIE). We analyzed data from 40,976 term births from three groups: 374 infants that developed HIE, 3,056 that developed fetal acidosis without HIE, and 37,546 healthy infants. We counted the transitions between FHR events and the length of FHR and UP events. Then, we used these features to train a random forest classifier to discriminate between the healthy and the pathological (acidosis or HIE) groups. Compared to the Caesarean delivery rates for each group, our system detected 6.9% more HIE cases (54.9% vs 61.8%, p<0.001) and 10.7% more acidosis cases (37.6% vs 48.3%, p<0.001), with no increase in the false positive rates in the healthy group (38.9% vs 38.8%, p=0.26). Importantly, over 3/4 of the HIE detections were made 3 hours or more before delivery. It is reasonable to expect that this would be enough lead time to permit clinical intervention to improve the outcome of birth.

Identifiers

PMID39364002
PMCPMC11448469

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.