Evidence map›Paper›PMID 39363915›Full record

ReviewMed-X2024

Microneedle sensors for dermal interstitial fluid analysis.

Gwangmook Kim, Hyunah Ahn, Joshua Chaj Ulloa, Wei Gao

Abstract readReview
In one paragraph

Review in Med-X, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

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  10. New Insights into Cardiac Intensive Care.Reviews in cardiovascular medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gwangmook KimAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA USA.
Hyunah AhnAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA USA.
Joshua Chaj UlloaAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA USA.
Wei GaoAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA USA.ORCID 0000-0002-8503-4562

Funding

Laser-Engraved Wearable Sweat Sensors to Detect and Monitor Cardiometabolic DiseaseR01HL155815 · NHLBI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI GAO, WEI · 2021 to 2025
$2.0M
UTSA ESTEEMED ProgramR25EB027605 · NIBIB · UNIVERSITY OF TEXAS SAN ANTONIO · PI ABU-LAIL, NEHAL IBRAHIM · 2019 to 2024
$1.6M
NHLBI NIH HHS R01 HL155815NIBIB NIH HHS R25 EB027605
6 · The paper itself

Abstract

The rapid advancement in personalized healthcare has driven the development of wearable biomedical devices for real-time biomarker monitoring and diagnosis. Traditional invasive blood-based diagnostics are painful and limited to sporadic health snapshots. To address these limitations, microneedle-based sensing platforms have emerged, utilizing interstitial fluid (ISF) as an alternative biofluid for continuous health monitoring in a minimally invasive and painless manner. This review aims to provide a comprehensive overview of microneedle sensor technology, covering microneedle design, fabrication methods, and sensing strategy. Additionally, it explores the integration of monitoring electronics for continuous on-body monitoring. Representative applications of microneedle sensing platforms for both monitoring and therapeutic purposes are introduced, highlighting their potential to revolutionize personalized healthcare. Finally, the review discusses the remaining challenges and future prospects of microneedle technology. Graphical Abstract:

Indexed as

BiosensorsInterstitial fluidMicroneedlesWearable

Identifiers

PMID39363915
PMCPMC11445365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.