ArticleBrain and behavior2024
Generalized spike-waves in idiopathic generalized epilepsies: Does their frequency matter?
Article in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Bloodletting as a harmful and misguided first-aid response to seizures in sub-saharan Africa: a case-based review.Epilepsy & behavior reports · 2026Article
- Global, regional, and national burden and trends of idiopathic epilepsy among children and adolescents from 1990 to 2021: insights from the global burden of disease study 2021.Annals of medicine · 2025Article
- Distinct spike-and-wave EEG profiles reveal susceptibility to fleeting/almost loss of consciousness (so-called blips) in generalized epilepsy.Epilepsia · 2025Article
- Generalized spike-waves in idiopathic generalized epilepsies: Does their frequency matter?Brain and behavior · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
objectivesWe hypothesized that the frequency (in Hertz) of generalized spike-waves (GSWs) in patients with idiopathic generalized epilepsy (IGE) has associations with the syndromic diagnosis as well as with the prognosis of patients (their response to medical treatment).
methodsThis was a retrospective study of a prospectively developed database. All patients with a diagnosis of IGE were studied at the epilepsy center at Shiraz University of Medical Sciences, Shiraz, Iran, from 2008 until 2022. Patients were classified into four IGE syndromes: childhood absence epilepsy; juvenile absence epilepsy; juvenile myoclonic epilepsy; and generalized tonic-clonic seizures alone.
resultsFive hundred and eighty-three patients were studied. GSWs were commonly observed in all four syndromes of IGE. Frequency of GSW (in Hertz) did not have a significant association with the syndromic diagnosis of the patients (p = .179). The presence of GSW did not have a significant association with the seizure outcome (becoming seizure free or not) of the patients (p = .416). Frequency of GSW did not have a significant association with the seizure outcome of the patients either (p = .574).
conclusionGSWs are the hallmark electroencephalographic footprints of idiopathic generalized epilepsies; however, neither their presence nor their frequency has practical associations with the syndromic diagnosis of IGEs or their outcome (response to treatment).
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