Evidence map›Paper›PMID 39363303›Full record

ArticleBMC women's health2024

Survey on adverse events associated with drug therapy for breast cancer patients.

Fumikata Hara, Reiko Nagasaki, Reiko Minami, Tadahiro Izutani, Takahiro Yoshida, Ayako Arai, Akiko Nihei, Naomi Sakurai, Shinji Ohno

Abstract read
In one paragraph

Article in BMC women's health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Preferences for electronic health information support concerning chemotherapy adverse reactions among young and middle-aged breast cancer patients based on the Kano model.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Article
  4. Study the impact ofCytotechnology · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fumikata HaraThe Cancer Institute Hospital Of JFCR, 3-8-31 Ariake, Koto-ku, Tokyo, Japan. fumikatahara@gmail.com.
Reiko NagasakiThe Cancer Institute Hospital Of JFCR, 3-8-31 Ariake, Koto-ku, Tokyo, Japan.
Reiko MinamiDaiichi Sankyo Co., Ltd, 3-5-1 Nihonbashi-honcho, Chuo-ku, Tokyo, Japan.
Tadahiro IzutaniDaiichi Sankyo Co., Ltd, 3-5-1 Nihonbashi-honcho, Chuo-ku, Tokyo, Japan.
Takahiro YoshidaDaiichi Sankyo Co., Ltd, 3-5-1 Nihonbashi-honcho, Chuo-ku, Tokyo, Japan.
Ayako AraiDaiichi Sankyo Co., Ltd, 3-5-1 Nihonbashi-honcho, Chuo-ku, Tokyo, Japan.
Akiko NiheiQLife, Inc, Toranomon33Mori-Bld. 10F, 3-8-21 Toranomon, Minato-ku, Tokyo, Japan.
Naomi SakuraiCancer Survivors Recruiting Project, General Incorporated Association, Daishin Building 4F-401, 2-9 Kanda Nishikicho, Chiyoda-ku, Tokyo, Japan.
Shinji OhnoSagara Hospital, Social Medical Corporation Hakuaikai, 3-31 Matsubara-cho, Kagoshima-shi, Kagoshima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the breast cancer treatment, there may be a gap between patients' information needs and physicians' perceptions. To address this issue, we conducted a comprehensive questionnaire survey aimed to assess the specific information needs of patients regarding the adverse events (AEs) associated with treatment.

methodsA web-based questionnaire survey (UMIN000049280: Registered on October 31, 2022) was conducted in patients with a history of breast cancer treatment. Responses were obtained regarding AEs experienced, AEs for which remedies were identified, AEs patients sought to prevent, and pre-treatment information on AEs patients desired to have.

resultsData from 435 breast cancer patients were analyzed. The most common AEs reported included hair loss (93.3%), malaise/fatigue (89.4%), nail changes (83.2%), dysgeusia (69.0%), leukopenia/white blood cell decreased (65.1%), neuropathy (62.3%), and nausea/vomiting (61.4%). Financial anxiety was reported in 35.2% of the participants. AEs for which a minority of patients found effective solutions included neuropathy (20.3%), financial anxiety (21.6%), edema (24.3%), joint pain (26.0%), and malaise/fatigue (26.7%). Patients expressed the greatest desire to avoid hair loss (34.7%), followed by nausea/vomiting (23.7%), interstitial lung disease/pneumonitis (5.5%), malaise/fatigue (5.1%), and dysgeusia (5.1%). The most commonly requested pre-treatment information regarding AEs was their duration, followed by prevention methods, management strategies, time to onset, and the impact on daily life.

conclusionsThis survey highlights the existence of significant unmet medical needs among breast cancer patients, due to the inadequate solutions available for managing AEs associated with various therapeutic agents. In addition, the survey revealed that patients have different information needs regarding different types of AEs.

Indexed as

Antineoplastic AgentsBreast NeoplasmsAdultAgedAlopeciaDrug-Related Side Effects and Adverse ReactionsDysgeusiaFatigueFemaleHumansMiddle AgedNauseaSurveys and QuestionnairesAntineoplastic AgentsAdverse eventsBreast cancerPatients’ needPROQuestionnaire survey

Identifiers

PMID39363303
PMCPMC11447999

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.