Evidence map›Paper›PMID 39363275›Full record

ArticleBMC oral health2024

Influence of light-polymerizing units and zirconia on the physical, chemical and biological properties of self-adhesive resin cements.

Siriwong Wongsirisuwan, Narin Intarak, Sasiprapa Prommanee, Noppadol Sa-Ard-Iam, Sunporn Namano, Dusit Nantanapiboon, Thantrira Porntaveetus

Abstract read
In one paragraph

Article in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Siriwong WongsirisuwanCenter of Excellence in Genomics and Precision Dentistry, Department of Physiology, Faculty of Dentistry, Chulalongkorn University, Bangkok, 10330, Thailand.
Narin IntarakCenter of Excellence in Genomics and Precision Dentistry, Department of Physiology, Faculty of Dentistry, Chulalongkorn University, Bangkok, 10330, Thailand.
Sasiprapa PrommaneeCenter of Excellence in Genomics and Precision Dentistry, Department of Physiology, Faculty of Dentistry, Chulalongkorn University, Bangkok, 10330, Thailand.
Noppadol Sa-Ard-IamImmunology Research Center, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
Sunporn NamanoImplant and Esthetic Dentistry Program, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
Dusit NantanapiboonDepartment of Operative Dentistry, Dental Material Research and Development Center, Faculty of Dentistry, University, Bangkok, Thailand.
Thantrira PorntaveetusCenter of Excellence in Genomics and Precision Dentistry, Department of Physiology, Faculty of Dentistry, Chulalongkorn University, Bangkok, 10330, Thailand. thantrira.p@chula.ac.th.

Funding

National Research Council of Thailand N42A650229This project was funded by the Health 66-101
6 · The paper itself

Abstract

backgroundSelf-adhesive resin cements (SARCs) are widely used for fixed prostheses, but incomplete cleaning near the gingival margin can cause inflammation. However, the factors influencing cement properties and the biological response of gingival fibroblasts to cement eluates are not well understood. This study examines the impact of two light-polymerizing units (LPUs) on the physical and chemical properties of two SARCs under simulated clinical conditions, as well as the subsequent response of human gingival fibroblasts (hGFs) to these eluates.

methodsDental cement discs of SARCs were polymerized using Kerr DemiPlus and 3 M Elipar DeepCure-S LED LPUs with or without a 2-mm thick zirconia screen. Physical properties (microhardness, surface roughness, residual monomers) were evaluated. hGFs' cell viability, wound healing potency, and gene expression were assessed.

resultsBoth Maxcem and RelyX exhibited reduced microhardness and increased surface roughness when polymerized through zirconia or with DemiPlus LPU. Higher residual monomers (HEMA and GDMA in Maxcem; TEGDMA in RelyX) concentration was observed with DemiPlus and zirconia polymerization. Maxcem polymerized with DemiPlus exhibited lower cell viability, impaired healing, and altered gene expression in hGFs compared to those polymerized with Elipar LPU. Gene expression changes included downregulated NRF2 and HO-1 and upregulated CCR-3.

conclusionsLight-polymerizing Maxcem through zirconia with DemiPlus LPU compromised SARCs' properties, leading to higher residual monomers and negatively impacting hGFs' viability, healing, and gene expression. Careful material selection and polymerization techniques are crucial to minimize adverse effects on surrounding tissues. CLINICAL SIGNIFICANCE: Clinicians should exercise caution when using LPUs and SARCs, especially when polymerizing through zirconia. This will help optimize the physical and chemical properties of SARCs and minimize potential adverse effects on the surrounding gingival soft tissues.

Indexed as

Cell SurvivalFibroblastsGingivaMaterials TestingResin CementsSurface PropertiesZirconiumBisphenol A-Glycidyl MethacrylateCells, CulturedCuring Lights, DentalHardnessHumansLight-Curing of Dental AdhesivesMethacrylatesPolyethylene GlycolsPolymerizationBisphenol A-Glycidyl Methacrylatehydroxyethyl methacrylateMaxcemMethacrylatesPolyethylene GlycolsPolymethacrylic AcidsResin Cementstriethylene glycol dimethacrylateZirconiumzirconium oxideCrownGDMAHEMAMicrohardnessPeriimplantitisPeriodontitisProsthesisResidual monomerResin cementSurface roughnessZirconia

Identifiers

PMID39363275
PMCPMC11451154

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.