Evidence map›Paper›PMID 39363035›Full record

ReviewCell biochemistry and biophysics2025

The Therapeutic Potential of Exosome Therapy in Sepsis Management: Addressing Complications and Improving Outcomes".

Payam Ali-Khiavi, Mahya Mohammadi, Sajjad Masoumi, Hossein Saffarfar, Reza Kheradmand, Ahmad Mobed, Faezeh Hatefnia

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cell biochemistry and biophysics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Payam Ali-KhiaviMedical faculty, Tabriz University of Medical Sciences, Tabriz, Iran.
Mahya MohammadiStudent Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sajjad MasoumiDepartment of Medical Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran.
Hossein SaffarfarCardiovascular Research Center, Tehran, Tehran University of Medical Sciences, Tehran, Iran.
Reza KheradmandSocial Determinants of Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Ahmad MobedSocial Determinants of Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Mobed1980@gmail.com.
Faezeh HatefniaSocial Determinants of Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Faezehhatefnia@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection occurs when pathogens penetrate tissues, reproduce, and trigger a host response to both the infectious agents and their toxins. A diverse array of pathogens, including viruses and bacteria, can cause infections. The host's immune system employs several mechanisms to combat these infections, typically involving an innate inflammatory response. Inflammation is a complex biological reaction that can affect various parts of the body and is a key component of the response to harmful stimuli. Sepsis arises when the body's response to infection leads to widespread damage to tissues and organs, potentially resulting in severe outcomes or death. The initial phase of sepsis involves immune system suppression. Early identification and targeted management are crucial for improving sepsis outcomes. Common treatment approaches include antibiotics, intravenous fluids, blood cultures, and monitoring urine output. This study explores the potential of exosome therapy in enhancing the management and alleviation of sepsis symptoms.

Indexed as

ExosomesSepsisAnimalsHumansBlood cellsExosome therapyInflammationMesenchymal stromal cellsSepsis

Identifiers

PMID39363035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.