Evidence map›Paper›PMID 39362962›Full record

Observational studyScientific reports2024

Performance of the 4C and SEIMC scoring systems in predicting mortality from onset to current COVID-19 pandemic in emergency departments.

Pedro Ángel de Santos Castro, Carlos Del Pozo Vegas, Leyre Teresa Pinilla Arribas, Daniel Zalama Sánchez, Ancor Sanz-García, Tony Giancarlo Vásquez Del Águila, Pablo González Izquierdo, Sara de Santos Sánchez, Cristina Mazas Pérez-Oleaga, Irma Domínguez Azpíroz and 2 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Pedro Ángel de Santos CastroEmergency Department, Hospital Clínico Universitario de Valladolid, Avenida de Ramón y Cajal, 3, 47003, Valladolid, Spain.
Carlos Del Pozo VegasEmergency Department, Hospital Clínico Universitario de Valladolid, Avenida de Ramón y Cajal, 3, 47003, Valladolid, Spain. cpozove@saludcastillayleon.es.
Leyre Teresa Pinilla ArribasEmergency Department, Hospital Clínico Universitario de Valladolid, Avenida de Ramón y Cajal, 3, 47003, Valladolid, Spain.
Daniel Zalama SánchezEmergency Department, Hospital Clínico Universitario de Valladolid, Avenida de Ramón y Cajal, 3, 47003, Valladolid, Spain.
Ancor Sanz-GarcíaFaculty of Health Sciences, University of Castilla la Mancha, Avda. Real Fábrica de Seda, s/n, 45600, Talavera de la Reina, Spain. ancor.sanz@gmail.com.
Tony Giancarlo Vásquez Del ÁguilaEmergency Department, Hospital Clínico Universitario de Valladolid, Avenida de Ramón y Cajal, 3, 47003, Valladolid, Spain.
Pablo González IzquierdoEmergency Department, Hospital Clínico Universitario de Valladolid, Avenida de Ramón y Cajal, 3, 47003, Valladolid, Spain.
Sara de Santos SánchezFaculty of Medicine, University of Valladolid, Valladolid, Spain.
Cristina Mazas Pérez-OleagaUniversidad Europea del Atlántico, Isabel Torres 21, 39011, Santander, Spain.
Irma Domínguez AzpírozUniversidad Europea del Atlántico, Isabel Torres 21, 39011, Santander, Spain.
Iñaki Elío PascualUniversidad Europea del Atlántico, Isabel Torres 21, 39011, Santander, Spain.
Francisco Martín-RodríguezFaculty of Medicine, University of Valladolid, Valladolid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evolution of the COVID-19 pandemic has been associated with variations in clinical presentation and severity. Similarly, prediction scores may suffer changes in their diagnostic accuracy. The aim of this study was to test the 30-day mortality predictive validity of the 4C and SEIMC scores during the sixth wave of the pandemic and to compare them with those of validation studies. This was a longitudinal retrospective observational study. COVID-19 patients who were admitted to the Emergency Department of a Spanish hospital from December 15, 2021, to January 31, 2022, were selected. A side-by-side comparison with the pivotal validation studies was subsequently performed. The main measures were 30-day mortality and the 4C and SEIMC scores. A total of 27,614 patients were considered in the study, including 22,361 from the 4C, 4,627 from the SEIMC and 626 from our hospital. The 30-day mortality rate was significantly lower than that reported in the validation studies. The AUCs were 0.931 (95% CI: 0.90-0.95) for 4C and 0.903 (95% CI: 086-0.93) for SEIMC, which were significantly greater than those obtained in the first wave. Despite the changes that have occurred during the coronavirus disease 2019 (COVID-19) pandemic, with a reduction in lethality, scorecard systems are currently still useful tools for detecting patients with poor disease risk, with better prognostic capacity.

Indexed as

COVID-19Emergency Service, HospitalSeverity of Illness IndexAdultAgedAged, 80 and overFemaleHumansLongitudinal StudiesMaleMiddle AgedPandemicsPrognosisRetrospective StudiesSpain4C mortality scoreCOVID-19 pandemicEmergency departmentMortalityScoring systemsSEIMC score

Identifiers

PMID39362962
PMCPMC11450147

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.