Evidence map›Paper›PMID 39362770›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2024

Correlation of FAPI PET Uptake with Immunohistochemistry in Explanted Lungs from Patients with Advanced Interstitial Lung Disease.

Masatoshi Hotta, Grace Hyun J Kim, Vilasinee Rerkpichaisuth, Pang Yu Teng, Wesley R Armstrong, Giuseppe Carlucci, Magnus Dahlbom, Fereidoun Abtin, Shahrzad M Lari, Gregory A Fishbein and 4 more

Abstract readClinical Trial
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Translational Theranostics in Glioblastoma: FAPI-46 as a Precision Medicine Tool.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  3. Article
  4. Head-to-head comparison ofEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Review
  6. FAP Expression in Renal Tumors Assessed by [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  7. Article
  8. EJNMMI research · 2025
    Article
  9. Article
  10. Article
  11. Fibroblast Activation Protein Inhibitor (FAPI)-Based Theranostics.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Masatoshi HottaAhmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, California; m.hotta.11.11@gmail.com.
Grace Hyun J KimDepartment of Radiological Sciences, David Geffen School of Medicine, UCLA, Los Angeles, California.
Vilasinee RerkpichaisuthDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine, UCLA, Los Angeles, California.
Pang Yu TengDepartment of Radiological Sciences, David Geffen School of Medicine, UCLA, Los Angeles, California.
Wesley R ArmstrongAhmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, California.
Giuseppe CarlucciAhmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, California.
Magnus DahlbomAhmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, California.
Fereidoun AbtinDepartment of Radiology, David Geffen School of Medicine, UCLA, Los Angeles, California.
Shahrzad M LariDivision of Pulmonary, Critical Care Medicine, Allergy, and Clinical Immunology, Department of Internal Medicine, David Geffen School of Medicine, UCLA, Los Angeles, California; and.
Gregory A FishbeinDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine, UCLA, Los Angeles, California.
Johannes CzerninAhmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, California.
Elizabeth R VolkmannDivision of Rheumatology, Department of Medicine, David Geffen School of Medicine, UCLA, Los Angeles, California.
S Sam WeigtDivision of Pulmonary, Critical Care Medicine, Allergy, and Clinical Immunology, Department of Internal Medicine, David Geffen School of Medicine, UCLA, Los Angeles, California; and.
Jeremie CalaisAhmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, California.

Funding

UCLA-Caltech Medical Scientist Training ProgramT32GM008042 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AJIJOLA, OLUJIMI A, DAWSON, DAVID WAYNE · 1985 to 2023
$29.9M
UCLA SPORE in Brain CancerP50CA211015 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Robert M Prins · 2017 to 2026
$25.2M
Identifying predictors of treatment response in systemic sclerosis-related interstitial lung diseaseK23HL150237 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VOLKMANN, ELIZABETH R · 2020 to 2024
$910k
NCI NIH HHS P50 CA211015NHLBI NIH HHS K23 HL150237NIGMS NIH HHS T32 GM008042
6 · The paper itself

Abstract

Recent studies have demonstrated promising results of fibroblast activation protein (FAP) inhibitor (FAPI) PET in prognosticating and monitoring interstitial lung diseases (ILDs). As a first step toward successful translation, our primary aim was to validate the FAPI PET uptake through immunohistochemistry in patients with advanced ILD who underwent lung transplantation after a FAPI PET scan.

Indexed as

ImmunohistochemistryLungLung Diseases, InterstitialPositron-Emission TomographyAgedBiological TransportEndopeptidasesFemaleFibroblast Activation Protein AlphaHumansLung TransplantationMaleMembrane ProteinsMiddle AgedQuinolines68Ga-FAPIEndopeptidasesFibroblast Activation Protein AlphaMembrane ProteinsQuinolinesFAPIimmunohistochemistryinterstitial lung diseaseslung transplantationPET

Identifiers

PMID39362770
PMCPMC11927094

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.