Evidence map›Paper›PMID 39362223›Full record

ArticleThe Lancet. Haematology2024

Radiation target nomenclature for lymphoma trials: consensus recommendations from the National Clinical Trials Network groups.

Omran Saifi, Chelsea C Pinnix, Leslie K Ballas, Chris R Kelsey, Sarah A Milgrom, Stephanie A Terezakis, Nicholas B Figura, Rahul R Parikh, John C Grecula, Stella Flampouri and 5 more

Abstract readConsensus Statement
In one paragraph

Article in The Lancet. Haematology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Omran SaifiDepartment of Radiation Oncology, Mayo Clinic, Jacksonville, FL, USA.
Chelsea C PinnixDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; NRG Oncology, Philadelphia, PA, USA.
Leslie K BallasNRG Oncology, Philadelphia, PA, USA; Department of Radiation Oncology, Cedars Sinai Medical Center, Los Angeles, CA, USA.
Chris R KelseyNRG Oncology, Philadelphia, PA, USA; Department of Radiation Oncology, Duke Cancer Institute, Durham, NC, USA.
Sarah A MilgromNRG Oncology, Philadelphia, PA, USA; Children's Oncology Group, Seattle, WA, USA; Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO, USA.
Stephanie A TerezakisNRG Oncology, Philadelphia, PA, USA; Children's Oncology Group, Seattle, WA, USA; Department of Radiation Oncology, University of Minnesota Medical School, Minneapolis, MN, USA.
Nicholas B FiguraDepartment of Radiation Oncology, Moffitt Cancer Center, Tampa, FL, USA; SWOG Cancer Research Network Group, Portland, OR, USA.
Rahul R ParikhNRG Oncology, Philadelphia, PA, USA; Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA; Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Cancer Research Group, Philadelphia, PA, USA.
John C GreculaDepartment of Radiation Oncology, The Ohio State University Medical Center, Columbus, OH, USA; Alliance for Clinical Trials in Oncology, Chicago, IL, USA.
Stella FlampouriNRG Oncology, Philadelphia, PA, USA; Children's Oncology Group, Seattle, WA, USA; Department of Radiation Oncology, Emory University, Atlanta, GA, USA.
Chul S HaSWOG Cancer Research Network Group, Portland, OR, USA; Department of Radiation Oncology, Mays Cancer Center, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Andrea C LoChildren's Oncology Group, Seattle, WA, USA; Department of Radiation Oncology, BC Cancer, Vancouver, BC, Canada; Department of Surgery, University of British Columbia, Vancouver, BC Canada; Canadian Cancer Trials Group, Kingston, ON, Canada.
John P PlastarasNRG Oncology, Philadelphia, PA, USA; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
David C HodgsonChildren's Oncology Group, Seattle, WA, USA; Canadian Cancer Trials Group, Kingston, ON, Canada; Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada; Department of Radiation Medicine, University of Toronto, Toronto, ON, Canada.
Bradford S HoppeDepartment of Radiation Oncology, Mayo Clinic, Jacksonville, FL, USA; NRG Oncology, Philadelphia, PA, USA; Children's Oncology Group, Seattle, WA, USA. Electronic address: hoppe.bradford@mayo.edu.

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
NRG Oncology Network Group Operations Center - GY9 BIQSFP Reports/BudgetsU10CA180868 · NCI · NRG ONCOLOGY FOUNDATION, INC. · PI NORMAN WOLMARK · 2014 to 2026
$206.8M
Member Site CoreU10CA180821 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI Evanthia Galanis · 2014 to 2026
$177.3M
Project-006U10CA180820 · NCI · ECOG-ACRIN MEDICAL RESEARCH FOUNDATION · PI Peter J ODwyer · 2014 to 2026
$167.6M
SWOG Network Group Operations Center of the NCTNU10CA180888 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI PRIMO N. LARA · 2014 to 2026
$152.1M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
OSU as a Network Lead Academic Participating Site for the NCI NCTNUG1CA233331 · NCI · OHIO STATE UNIVERSITY · PI John L. Hays, Dwight H. Owen · 2019 to 2026
$8.9M
NCI NIH HHS U10 CA180820NCI NIH HHS U10 CA180821NCI NIH HHS U10 CA180868NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180888NCI NIH HHS U10 CA180899NCI NIH HHS UG1 CA233331
6 · The paper itself

Abstract

Contemporary lymphoma radiation target volumes that rely on post-systemic therapy imaging do not have standardised nomenclature. A forum of radiation oncology lymphoma leaders from the National Clinical Trials Network groups (NRG Oncology, Children's Oncology Group, SWOG Cancer Research Network, Alliance for Clinical Trials in Oncology, Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Cancer Research Group, and the Canadian Cancer Trials Group) was convened and established standardised nomenclature for these volumes in the autumn of 2024. Involved-site radiotherapy includes the full cranial-caudal extent of prechemotherapy disease and takes into account axial anatomical changes only. Residual site radiotherapy targets only the postchemotherapy CT-anatomical mass. PET-directed radiotherapy exclusively targets PET-positive disease and includes three types: PET-directed involved site radiotherapy using the superior-inferior aspect of prechemotherapy involved disease sites that remain PET-avid on post-treatment imaging; PET-directed residual site radiotherapy using only the postchemotherapy CT-anatomical residual mass that contains the PET-avid lesion on post-treatment imaging, without excluding sites that had complete metabolic response; and PET-directed residual PET radiotherapy using only the PET-avid focus, irrespective of the corresponding adjacent non-PET-avid CT-anatomical disease surrounding it.

Indexed as

Clinical Trials as TopicLymphomaHumansPositron-Emission TomographyTerminology as Topic

Identifiers

PMID39362223
PMCPMC11635836

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.