Evidence map›Paper›PMID 39361645›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Lipopeptide antibiotics disrupt interactions of undecaprenyl phosphate with UptA.

Abraham O Oluwole, Neha V Kalmankar, Michela Guida, Jack L Bennett, Giovanna Poce, Jani R Bolla, Carol V Robinson

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. ThemBio · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Lipopeptide antibiotics disrupt interactions of undecaprenyl phosphate with UptA.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abraham O OluwoleDepartment of Chemistry, University of Oxford, Oxford OX1 3QZ, United Kingdom.ORCID 0000-0001-8647-4781
Neha V KalmankarDepartment of Chemistry, University of Oxford, Oxford OX1 3QZ, United Kingdom.ORCID 0000-0003-4834-3566
Michela GuidaThe Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford OX1 3QU, United Kingdom.ORCID 0000-0001-6487-1495
Jack L BennettDepartment of Chemistry, University of Oxford, Oxford OX1 3QZ, United Kingdom.
Giovanna PoceDepartment of Chemistry and Technologies of Drug, Sapienza University of Rome, Rome 00185, Italy.ORCID 0000-0001-7466-8861
Jani R BollaThe Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford OX1 3QU, United Kingdom.ORCID 0000-0003-4346-182X
Carol V RobinsonDepartment of Chemistry, University of Oxford, Oxford OX1 3QZ, United Kingdom.ORCID 0000-0001-7829-5505

Funding

Royal Society (The Royal Society) URF\R1\211567UKRI | Medical Research Council (MRC) MR/V028839/1Wellcome TrustWellcome Trust (WT) 221795/Z/20/Z
6 · The paper itself

Abstract

The peptidoglycan pathway represents one of the most successful antibacterial targets with the last critical step being the flipping of carrier lipid, undecaprenyl phosphate (C

Indexed as

Anti-Bacterial AgentsBacillus subtilisBacterial ProteinsPolyisoprenyl PhosphatesEscherichia coliLipopeptidesMembrane ProteinsProtein BindingAnti-Bacterial AgentsBacterial ProteinsLipopeptidesMembrane ProteinsPolyisoprenyl Phosphatesundecaprenyl phosphatenative mass spectrometrypeptidoglycanundecaprenyl phosphate transporter AUptA

Identifiers

PMID39361645
PMCPMC11474028

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.