Evidence map›Paper›PMID 39361530›Full record

ArticleNano letters2024

Distinguishing Protein Corona from Nanoparticle Aggregate Formation in Complex Biological Media Using X-ray Photon Correlation Spectroscopy.

Caroline E P Silva, Agustin S Picco, Flavia Elisa Galdino, Mariangela de Burgos Martins de Azevedo, Marilina Cathcarth, Aline R Passos, Mateus Borba Cardoso

Abstract read
In one paragraph

Article in Nano letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Caroline E P SilvaBrazilian Synchrotron Light Laboratory (LNLS), Brazilian Center for Research in Energy & Materials (CNPEM), Campinas, Sao Paulo 13083-970, Brazil.ORCID 0000-0001-7495-9335
Agustin S PiccoInstituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (INIFTA), Facultad de Ciencias Exactas, Universidad Nacional de La Plata - CONICET, 1900 La Plata, Argentina.
Flavia Elisa GaldinoBrazilian Synchrotron Light Laboratory (LNLS), Brazilian Center for Research in Energy & Materials (CNPEM), Campinas, Sao Paulo 13083-970, Brazil.ORCID 0000-0002-7799-3077
Mariangela de Burgos Martins de AzevedoBrazilian Synchrotron Light Laboratory (LNLS), Brazilian Center for Research in Energy & Materials (CNPEM), Campinas, Sao Paulo 13083-970, Brazil.
Marilina CathcarthInstituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (INIFTA), Facultad de Ciencias Exactas, Universidad Nacional de La Plata - CONICET, 1900 La Plata, Argentina.ORCID 0000-0002-1062-0954
Aline R PassosBrazilian Synchrotron Light Laboratory (LNLS), Brazilian Center for Research in Energy & Materials (CNPEM), Campinas, Sao Paulo 13083-970, Brazil.
Mateus Borba CardosoBrazilian Synchrotron Light Laboratory (LNLS), Brazilian Center for Research in Energy & Materials (CNPEM), Campinas, Sao Paulo 13083-970, Brazil.ORCID 0000-0003-2102-1225

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In biological systems, nanoparticles interact with biomolecules, which may undergo protein corona formation that can result in noncontrolled aggregation. Therefore, comprehending the behavior and evolution of nanoparticles in the presence of biological fluids is paramount in nanomedicine. However, traditional lab-based colloid methods characterize diluted suspensions in low-complexity media, which hinders in-depth studies in complex biological environments. Here, we apply X-ray photon correlation spectroscopy (XPCS) to investigate silica nanoparticles (SiO

Indexed as

NanoparticlesProtein CoronaSilicon DioxideColloidsPhotonsSurface PropertiesColloidsProtein CoronaSilicon DioxideAggregationProtein CoronaSilica NanoparticlesX-ray Photon Correlation Spectroscopy (XPCS)

Identifiers

PMID39361530
PMCPMC11505373

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.