Evidence map›Paper›PMID 39361224›Full record

ArticleGeneral thoracic and cardiovascular surgery2025

Impact of waitlist weight change on outcomes in heart transplant recipients: a UNOS database analysis.

Melissa A Austin, Danial Ahmad, Jake L Rosen, Matthew P Weber, Indranee Rajapreyar, Jesus Eduardo Rame, Rene J Alvarez, John W Entwistle, Howard T Massey, Vakhtang Tchantchaleishvili

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Article in General thoracic and cardiovascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Melissa A AustinDivision of Cardiac Surgery, Thomas Jefferson University, 1025 Walnut Street, College Building, Suite 607, Philadelphia, PA, 19107, USA.
Danial AhmadDivision of Cardiac Surgery, Thomas Jefferson University, 1025 Walnut Street, College Building, Suite 607, Philadelphia, PA, 19107, USA.
Jake L RosenDivision of Cardiac Surgery, Thomas Jefferson University, 1025 Walnut Street, College Building, Suite 607, Philadelphia, PA, 19107, USA.
Matthew P WeberDivision of Cardiac Surgery, Thomas Jefferson University, 1025 Walnut Street, College Building, Suite 607, Philadelphia, PA, 19107, USA.
Indranee RajapreyarDivision of Cardiology, Thomas Jefferson University, Philadelphia, PA, USA.
Jesus Eduardo RameDivision of Cardiology, Thomas Jefferson University, Philadelphia, PA, USA.
Rene J AlvarezDivision of Cardiology, Thomas Jefferson University, Philadelphia, PA, USA.
John W EntwistleDivision of Cardiac Surgery, Thomas Jefferson University, 1025 Walnut Street, College Building, Suite 607, Philadelphia, PA, 19107, USA.
Howard T MasseyDivision of Cardiac Surgery, Thomas Jefferson University, 1025 Walnut Street, College Building, Suite 607, Philadelphia, PA, 19107, USA.
Vakhtang TchantchaleishviliDivision of Cardiac Surgery, Thomas Jefferson University, 1025 Walnut Street, College Building, Suite 607, Philadelphia, PA, 19107, USA. Vakhtang.tchantchaleishvili@jefferson.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile the effect of pre-transplant weight on patient outcomes following heart transplantation (HTx) has previously been studied, data regarding the impact of dynamic weight change prior to HTx are extremely limited.

objectivesWe sought to elucidate the interaction between HTx listing weight and weight change while waitlisted, and explore how that interaction impacts post-HTx survival in a continuous manner.

methodsAdult patients listed for HTx from 1987 to 2020 were identified from UNOS database. Three-dimensional restricted cubic spline analysis explored post-HTx survival relative to both changes in BMI/weight and BMI at time of HTx listing. Continuous predictor variables were analyzed with Cox proportional hazards method.

results9,628 included patients underwent HTx. Median recipient age was 55 [IQR 46-62] years, and 21% were females. 53% of patients lost while 47% gained weight on the waitlist. Median BMI (27.6 kg/m

conclusionsImpact of weight change varies depending on listing BMI. While a survival benefit is seen in non-obese patients who gain some weight, significant weight loss is associated with poorer survival.

Indexed as

Heart FailureHeart TransplantationWaiting ListsWeight GainWeight LossAdultBody Mass IndexDatabases, FactualFemaleHumansMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsCardiac cachexiaDatabaseHeart failureHeart transplantationObesityWeight gainWeight loss

Identifiers

PMID39361224
PMCPMC11993457

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