Evidence map›Paper›PMID 39361165›Full record

ArticleCancer causes & control : CCC2025

Prevalence and concordance of penile, anal, and oral human papillomavirus infections among sexually active heterosexual men in Ibadan, Nigeria.

Imran O Morhason-Bello, Kathy Baisley, Miquel Angel Pavon, Isaac F Adewole, Rasheed Bakare, Sikiru A Adebayo, Silvia de Sanjosé, Suzanna C Francis, Deborah Watson-Jones

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Article in Cancer causes & control : CCC, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Imran O Morhason-BelloObstetrics and Gynaecology Department, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Ibadan, Oyo, Nigeria. imranmorhasonbello@gmail.com.ORCID https://orcid.org/0000-0002-7448-4824
Kathy BaisleyDepartment of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK.
Miquel Angel PavonInfection and Cancer Laboratory, Cancer Epidemiology Research Program, ICO Barcelona, Spain, Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Bellvitge Biomedical Research Institute (IDIBELL), Gran Via de l'Hospitalet, 199-203, 08908, L'Hospitalet de Llobregat, Barcelona, Spain.
Isaac F AdewoleObstetrics and Gynaecology Department, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Ibadan, Oyo, Nigeria.
Rasheed BakareDepartment of Microbiology, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Sikiru A AdebayoUrological Division, Department of Surgery, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Silvia de SanjoséDivision of Cancer Epidemiology and Genetics, Medical Center Drive, National Cancer Institute, Rockville, Baltimore, MD, 9609, USA.
Suzanna C FrancisDepartment of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK.
Deborah Watson-JonesMwanza Intervention Trials Unit, National Institute for Medical Research, Mwanza, Tanzania.

Funding

Epigenetic study of oral HPV infection-associated oral cancer in people living with HIV in NigeriaR01CA274952 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HOU, LIFANG, MORHASON - BELLO, IMRAN · 2022 to 2025
$3.3M
NCI NIH HHS R01 CA274952
6 · The paper itself

Abstract

backgroundThe data on epidemiology of Human papillomavirus (HPV) infections in men are scarce relative to women generally, particularly among men engaging in heterosexual relationships. This study investigated the prevalence and risk factors for penile, anal, and oral HPV in men in two communities in Ibadan, Nigeria.

methodsThis was a cross-sectional survey involving a face-to-face interview, a clinical examination, and sample collection from participants. HPV genotyping was performed with Anyplex II 28 HPV assay. The prevalences and factors associated with HPV infections using multivariable models and concordance between sites.

resultsOf 316 men, the proportion of any HPV infection in the penile, anal, and oral sites was 40.5%, 9.7%, and 7.8%, respectively. The proportion of any high-risk HPV, low-risk HPV, and multiple HPV infections was highest in the penis followed by the anal and oral sites. Only 5/316 (1.6%) men had concordant HPV in all three sites, with the highest concordance in penile-anal sites relative to penile-oral and anal-oral sites. The odds of penile HPV were higher in men aged 25 years and above. Having penile HPV was associated with higher odds of detecting anal HPV and vice versa. Oral HPV was less likely in men not living with their sexual partners.

conclusionPenile HPV is the most common infection followed by anal HPV and oral HPV infections among heterosexual Nigerian men. Concordant HPV infections was highest in penile-anal sites. Nigerian men, as in other settings, are a reservoir of HPV and it is important to conduct more robust studies to appreciate their role in HPV transmission, epidemiology, and prevention.

Indexed as

Anus DiseasesHeterosexualityMouth DiseasesPapillomavirus InfectionsAdolescentAdultAnal CanalCross-Sectional StudiesHumansMaleMiddle AgedNigeriaPapillomaviridaePrevalenceRisk FactorsSexual BehaviorAnalAno-genital or oro-genitalConcordanceHPVMenNigeriaOral human papillomavirusPenilePrevalence

Identifiers

PMID39361165

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.