Evidence map›Paper›PMID 39361081›Full record

GuidelineIntensive care medicine2024

European Society of Intensive Care Medicine guidelines on end of life and palliative care in the intensive care unit.

Jozef Kesecioglu, Katerina Rusinova, Daniela Alampi, Yaseen M Arabi, Julie Benbenishty, Dominique Benoit, Carole Boulanger, Maurizio Cecconi, Christopher Cox, Marjel van Dam and 44 more

Abstract readPractice Guideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Intensive care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  2. Guideline
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  5. [S3 guideline on sepsis-prevention, diagnosis, therapy, and follow-up care-update 2025].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

54 authors.

Jozef KeseciogluDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. j.kesecioglu@umcutrecht.nl.
Katerina RusinovaDepartment of Palliative Medicine, 1st Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czechia.
Daniela AlampiSapienza University of Rome, A.O.U. Sant'Andrea, Rome, Italy.
Yaseen M ArabiIntensive Care Department, King Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.
Julie BenbenishtyFaculty of Medicine, School of Nursing, Hebrew University, Jerusalem, Israel.
Dominique BenoitDepartment of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium.
Carole BoulangerRoyal Devon University NHS Foundation Trust, Exeter, UK.
Maurizio CecconiBiomedical Sciences Department, Humanitas University, Milan, Italy.
Christopher CoxDivision of Pulmonary and Critical Care Medicine, Duke University, Durham, NC, USA.
Marjel van DamDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Diederik van DijkDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
James DownarDepartment of Medicine, University of Ottawa, Ottawa, Canada.
Nikolas EfstathiouSchool of Nursing and Midwifery, University of Birmingham, Birmingham, UK.
Ruth EndacottNational Institute for Health and Care Research, London, UK.
Alessandro GalazziDepartment of Medicine, University of Udine, Udine, Italy.
Fiona van GelderGelderse Vallei Hospital, Ede, The Netherlands.
Rik T GerritsenCentrum Voor Intensive Care, Medisch Centrum Leeuwarden, Leeuwarden, The Netherlands.
Armand GirbesDepartment of Critical Care, AmsterdamUMC Location VUmc, Amsterdam, The Netherlands.
Laura HawyrluckInterdepartmental Division Critical Care Medicine, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Canada.
Margaret HerridgeCritical Care and Respiratory Medicine, University Health Network, Toronto General Research Institute, Toronto, Canada.
Jan HudecDepartment of Anaesthesiology and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czechia.
Nancy Kentish-BarnesFamiréa Research Group, APHP Nord, Saint Louis Hospital, Intensive Care Unit, Paris, France.
Monika KerckhoffsDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Jos M LatourSchool of Nursing and Midwifery, Faculty of Health, University of Plymouth, Plymouth, UK.
Jan MalaskaDepartment of Simulation Medicine, Faculty of Medicine, Masaryk University, Brno, Czechia.
Annachiara MarraDepartment of Neuroscience, Reproductive Science and Dentistry, University of Naples, Naples, Italy.
Stephanie Meddick-DysonWolfson Palliative Care Research Centre, Hull York, Medical School, University of Hull, Hull, UK.
Spyridon MentzelopoulosFirst Department of Intensive Care Medicine, National and Kapodistrian University of Athens Medical School, Evaggelismos General Hospital, Athens, Greece.
Mervyn MerDepartment of Medicine, Divisions of Critical Care and Pulmonology, Charlotte Maxeke Johannesburg Academic Hospital (CMJAH), Johannesburg, South Africa.
Victoria MetaxaDepartment of Critical Care, King's College Hospital NHS Foundation Trust, London, UK.
Andrej MichalsenDepartment of Anesthesiology, Critical Care, Emergency Medicine and Pain Therapy, Konstanz Hospital, Constance, Germany.
Rajesh MishraAhmedabad Shaibya Comprehensive Care Clinic, Ahmedabad, India.
Giovanni MistralettiDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
Margo van MolDepartment of Intensive Care Adults, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands.
Rui MorenoHospital de São José, Unidade Local de Saúde São José, Lisbon, Portugal.
Judith NelsonMemorial Hospital, Weill Cornell Medical College, New York, NY, USA.
Andrea Ortiz SuñerHospital Arnau de Vilanova-Lliria, Valencia, Spain.
Natalie PattisonUniversity of Hertfordshire, East and North Hertfordshire NHS Trust, Hatfield, UK.
Tereza ProkopovaDepartment of Anaesthesiology and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czechia.
Kathleen PuntilloSchool of Nursing, University of California, San Francisco, San Francisco, CA, USA.
Kathryn PuxtyIntensive Care, Glasgow Royal Infirmary, Glasgow, UK.
Samah Al QahtaniIntensive Care Department, King Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.
Lukas RadbruchDepartment of Palliative Medicine, University Hospital Bonn, Bonn, Germany.
Emilio Rodriguez-RuizDepartment of Intensive Care Medicine, University Clinic Hospital of Santiago de Compostela (CHUS), Galician Public Health System (SERGAS), Santiago de Compostela, Spain.
Ron SabarSabar Health, Netanya, Israel.
Stefan J SchallerDepartment of Anaesthesiology and Intensive Care Medicine (CCM/CVK), Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany.
Shahla SiddiquiDepartment of Anesthesia Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Charles L SprungDepartment of Anesthesiology, Critical Care Medicine and Pain, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Michele UmbrelloS.C. Anesthesia and Intensive Care, Legnano Hospital, ASST Ovest Milanese, Milan, Italy.
Marco VerganoDepartment of Anesthesia, Intensive Care and Emergency, San Giovanni Bosco Hospital, Turin, Italy.
Massimo ZambonAnesthesia and Intensive Care Ospedale "Uboldo", Cernusco sul Naviglio, Milan, Italy.
Marieke ZegersDepartment of Intensive Care, Radboud University Medical Center, Nijmegen, The Netherlands.
Michael DarmonMédecine Intensive et Réanimation, APHP, Saint-Louis Hospital, Paris, France.
Elie AzoulayMédecine Intensive et Réanimation, APHP, Saint-Louis Hospital, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The European Society of Intensive Care Medicine (ESICM) has developed evidence-based recommendations and expert opinions about end-of-life (EoL) and palliative care for critically ill adults to optimize patient-centered care, improving outcomes of relatives, and supporting intensive care unit (ICU) staff in delivering compassionate and effective EoL and palliative care. An international multi-disciplinary panel of clinical experts, a methodologist, and representatives of patients and families examined key domains, including variability across countries, decision-making, palliative-care integration, communication, family-centered care, and conflict management. Eight evidence-based recommendations (6 of low level of evidence and 2 of high level of evidence) and 19 expert opinions were presented. EoL legislation and the importance of respecting the autonomy and preferences of patients were given close attention. Differences in EoL care depending on country income and healthcare provision were considered. Structured EoL decision-making strategies are recommended to improve outcomes of patients and relatives, as well as staff satisfaction and mental health. Early integration of palliative care and the use of standardized tools for symptom assessment are suggested for patients at high risk of dying. Communication training for ICU staff and printed communication aids for families are advocated to improve outcomes and satisfaction. Methods for enhancing family-centeredness of care include structured family conferences and culturally sensitive interventions. Conflict-management protocols and strategies to prevent burnout among healthcare professionals are also considered. The work done to develop these guidelines highlights many areas requiring further research.

Indexed as

Intensive Care UnitsPalliative CareTerminal CareCommunicationCritical CareDecision MakingEuropeHumansSocieties, MedicalCommunicationConflict managementCultural variationsDecision-makingEnd of lifeFamily-centered careGRADEIntensive care unitPalliative care

Identifiers

PMID39361081
PMCPMC11541285

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.