Evidence map›Paper›PMID 39360974›Full record

SynthesisSchizophrenia bulletin2025

Emotion Processing and Its Relationship to Social Functioning and Symptoms in Psychotic Disorder: A Systematic Review and Meta-analysis.

Sean Murrihy, Kate Filia, Sue Cotton, Lisa Phillips, Sarah Youn, Anuradhi Jayasinghe, Anna Wrobel, Eslam M Bastawy, Kelly Allott, Amity Watson

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Schizophrenia bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sean MurrihyMelbourne School of Psychological Sciences, University of Melbourne, Melbourne 3052, Australia.
Kate FiliaOrygen, Melbourne 3052, Australia.
Sue CottonOrygen, Melbourne 3052, Australia.
Lisa PhillipsMelbourne School of Psychological Sciences, University of Melbourne, Melbourne 3052, Australia.
Sarah YounOrygen, Melbourne 3052, Australia.ORCID 0000-0002-6477-2806
Anuradhi JayasingheOrygen, Melbourne 3052, Australia.
Anna WrobelOrygen, Melbourne 3052, Australia.
Eslam M BastawyIMPACT, The Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong 3220, Australia.
Kelly AllottOrygen, Melbourne 3052, Australia.ORCID 0000-0002-0640-4634
Amity WatsonOrygen, Melbourne 3052, Australia.

Funding

Australian Government Research Training Program Scholarship
6 · The paper itself

Abstract

backgroundEmotion processing (EP) is impaired in individuals with psychosis and associated with social functioning; however, it is unclear how symptoms fit into this relationship. The aim of this systematic review and meta-analysis was to examine interrelationships between EP, symptoms, and social functioning, test whether different symptom domains mediate the relationship between EP and social functioning, and examine the moderating effects of illness stage and EP task type. STUDY

designMEDLINE, Embase, and PsycINFO databases were searched for studies that included individuals with psychosis and reported correlations between EP, symptom domains (positive, negative, depressive, and disorganization), and social functioning. Random effects meta-analyses determined the strength of correlations, and subgroup analyses included illness stage and EP task type (lower- vs higher-level processing). Meta-analytic structural equation models tested whether symptom domains mediated the relationship between EP and social functioning.

resultsThere was a small relationship (r = .18) between EP and social functioning. Positive, negative, and disorganization symptoms mediated this relationship, although indirect effects were small. Higher-level EP tasks were more strongly associated with negative symptoms than lower-level tasks. Relationships between EP and both social functioning and positive symptoms were smaller in the first episode of psychosis than in established illness.

conclusionsThe mediating relationship suggests that EP not only influences social dysfunction directly but contributes to negative and disorganization symptoms, which in turn impair social functioning. This pathway suggests that targeting negative and disorganization symptoms may ultimately improve social outcomes for individuals with psychosis. Future research, particularly in early psychosis, is needed to determine other factors impacting these interrelationships.

Indexed as

EmotionsPsychosocial FunctioningPsychotic DisordersSchizophreniaHumansdepressive symptomsdisorganization symptomsfirst episode psychosisnegative symptomspositive symptomsschizophreniasocial cognition

Identifiers

PMID39360974
PMCPMC12236351

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.