Evidence map›Paper›PMID 39360029›Full record

ReviewExperimental biology and medicine (Maywood, N.J.)2024

Single-cell RNA sequencing data locate ALDH1A2-mediated retinoic acid synthetic pathway to glomerular parietal epithelial cells.

Wen-Bin Liu, Damian Fermin, An-Long Xu, Jeffrey B Kopp, Qihe Xu

Abstract readReview
In one paragraph

Review in Experimental biology and medicine (Maywood, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wen-Bin LiuBeijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Damian FerminDepartment of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, United States.
An-Long XuBeijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Jeffrey B KoppKidney Disease Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Qihe XuRenal Sciences and Integrative Chinese Medicine Laboratory, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom.

Funding

FOCAL SEGMENTAL GLOMERULOSCLEROSIS--PATHOGENESIS AND TREATMENTZ01DK043308 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI KOPP, JEFFREY BURNETT · 1997 to 2008
$1.0M
Intramural NIH HHS Z01 DK043308
6 · The paper itself

Abstract

Aldehyde dehydrogenase 1, family member A2, is a retinoic acid-synthesizing enzyme encoded by

Indexed as

Aldehyde Dehydrogenase 1 FamilyEpithelial CellsRetinal DehydrogenaseSingle-Cell AnalysisTretinoinAnimalsHumansKidney GlomerulusMiceSequence Analysis, RNAAldehyde Dehydrogenase 1 FamilyALDH1A2 protein, humanAldh1a2 protein, mouseRetinal DehydrogenaseTretinoinacute kidney injuryAldh1a2chronic kidney diseaseparietal epithelial cellsrapidly progressive glomerulonephritisretinoic acidscRNA-seqsnRNA-seq

Identifiers

PMID39360029
PMCPMC11444976

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.