Evidence map›Paper›PMID 39359774›Full record

ReviewAnnals of medicine and surgery (2012)2024

Intestinal microbiome as a diagnostic marker of coronary artery disease: a systematic review and meta-analysis.

Yomna E Dean, Mohamed A Shebl, Mohamed Doma, Rafeek W Elmezayen, Jose J Loayza Pintado, Samah S Rouzan, Noheir Ashraf Ibrahem Fathy Hassan, Yasmeen E Yaqout, Akiko Tokunaga, Chukwuebuka Anozie and 9 more

Abstract readReview
In one paragraph

Review in Annals of medicine and surgery (2012), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yomna E DeanAlexandria University, Faculty of Medicine, Alexandria.
Mohamed A SheblFaculty of Medicine, Cairo University, Kasr Al- Ainy, Cairo.
Mohamed DomaAlexandria University, Faculty of Medicine, Alexandria.ORCID https://orcid.org/0009-0006-1915-0174
Rafeek W ElmezayenKafr-elsheikh University, Kafr-elsheikh.
Jose J Loayza PintadoUniversity for Texas Rio Grande Valley, McAllen, Texas.
Samah S RouzanAlexandria University, Faculty of Medicine, Alexandria.
Noheir Ashraf Ibrahem Fathy HassanAswan University, Faculty of Medicine, Aswan.
Yasmeen E YaqoutAlexandria University, Faculty of Medicine, Alexandria.
Akiko TokunagaSapporo Medical University, Sapporo, Japan.
Chukwuebuka AnozieWindsor University School of Medicine, St. Kitts and Nevis, Caribbean.
Omar ElKoumiSuez Universtiy, Faculty of Medicine, Suez, Egypt.
Sameh S ElawadyMedical University of South Carolina.
Tamer MadyInternational American University, College of Medicine, Saint Lucia.
Sana N NizamUniversity of California Los Angeles, California.
Yasser EtmanTexas Health Hospital Rockwall, Director of Intensive Care Unit, Rockwall, Texas, USA.
Rayees NizamKafr-elsheikh University, Kafr-elsheikh.
Yusef HazimehLebanese University.ORCID https://orcid.org/0000-0002-5090-5997
Mohamed AlazmyMinistry of Health, Medical Director, Kuwait.
Hani AiashSuez Universtiy, Faculty of Medicine, Suez, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The intestinal microbiome has been recently linked to several metabolic and chronic disorders, one of which is coronary artery disease (CAD). Our study aimed to analyze the intestinal microbiome of CAD patients and assess the eligibility of dysbiosis as a diagnostic marker of CAD. Methods: PubMed, Scopus, Embase, and Web of Science were searched using terms, such as 'CAD' and 'microbiome'. Only observational controlled studies were included. R version 4.2.2 was used for the analysis. Results: A significant association was found between the CAD group and increased Simpson and Shannon Indices compared with the control group (MD=0.04, 95% CI=0.03-0.05, and MD=0.11, 95% CI=0.01-0.22, respectively). Our analysis yielded a statistically significant association between the CAD group and increased Prevotella genus (MD=13.27, 95% CI=4.12-22.42, Conclusion: Dysbiosis is an acceptable diagnostic marker of CAD. Decreased

Indexed as

coronary artery diseasedysbiosisgastrointestinal microbiomemicrobiota

Identifiers

PMID39359774
PMCPMC11444608

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.