Evidence map›Paper›PMID 39359716›Full record

ArticleClinical psychological science : a journal of the Association for Psychological Science2024

Neuroticism Is Prospectively Associated With 30-Month Changes in Broadband Internalizing Symptoms, but Not Narrowband Positive Affect or Anxious Arousal, in Emerging Adulthood.

Christopher C Conway, Shannon E Grogans, Allegra S Anderson, Samiha Islam, Logan E Craig, Jazmine Wedlock, Juyoen Hur, Kathryn A DeYoung, Alexander J Shackman

Abstract read
In one paragraph

Article in Clinical psychological science : a journal of the Association for Psychological Science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. A Shared Threat-Anticipation Circuit Is Dynamically Engaged at Different Moments by Certain and Uncertain Threat.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christopher C ConwayDepartment of Psychology, Fordham University, Bronx, New York, USA.ORCID 0000-0002-6848-2638
Shannon E GrogansDepartment of Psychology, University of Maryland, College Park, MD 20742 USA.ORCID 0000-0003-0383-4601
Allegra S AndersonDepartment of Psychological Sciences, Vanderbilt University, Nashville, TN 37240 USA.ORCID 0000-0002-0961-9016
Samiha IslamDepartment of Psychology, University of Pennsylvania, Philadelphia, PA USA.ORCID 0000-0003-3238-7740
Logan E CraigSchool of Education, University of Tennessee at Chattanooga, Chattanooga, TN, USA.
Jazmine WedlockDepartment of Human Development and Quantitative Methodology, University of Maryland, College Park, MD 20742 USA.
Juyoen HurDepartment of Psychology, Yonsei University, Seoul 03722, Republic of Korea.ORCID 0000-0002-6961-5199
Kathryn A DeYoungDepartment of Human Development and Quantitative Methodology, University of Maryland, College Park, MD 20742 USA.ORCID 0000-0002-3904-7979
Alexander J ShackmanDepartment of Psychology, University of Maryland, College Park, MD 20742 USA.ORCID 0000-0002-3629-4704

Funding

LIFE-SPAN DEVELOPMENT OF NORMAL AND ABNORMAL BEHAVIORT32MH018921 · NIMH · VANDERBILT UNIVERSITY · PI HUMPHREYS, KATHRYN LEIGH · 1989 to 2024
$6.7M
Using Theory- and Data-Driven Neurocomputational Approaches and Digital Phenotyping to Understand RDoC Acute and Potential ThreatR01MH131264 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI ALEXANDER JOSEPH SHACKMAN · 2022 to 2026
$3.9M
Using Multimodal Neuroimaging and Real-World Experience Sampling to Understand Negative Affect and Paranoid Ideation in PsychosisR01MH121409 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI BLANCHARD, JACK J., SHACKMAN, ALEXANDER JOSEPH · 2020 to 2024
$3.7M
A Prospective-Longitudinal Investigation of the Biopsychosocial Predictors of Loneliness Across Adolescence in Autism and Typical DevelopmentR01MH125370 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI REDCAY, ELIZABETH · 2021 to 2025
$3.6M
Prospective Determination of Neurobehavioral Risk for the Development of Emotion DisordersR01MH107444 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI SHACKMAN, ALEXANDER JOSEPH · 2016 to 2020
$3.4M
Using Computational Neuroimaging and Extended Smartphone Assessment to Understand the Pathways Linking Threat-Related Brain Circuits to Alcohol Misuse Across AdulthoodR01AA030042 · NIAAA · UNIV OF MARYLAND, COLLEGE PARK · PI ALEXANDER JOSEPH SHACKMAN · 2023 to 2026
$2.5M
Using Functional Neuroimaging and Smartphone Digital Phenotyping to Understand the Emergence of Internalizing IllnessF31MH132280 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI GROGANS, SHANNON · 2023 to 2024
$97k
NIAAA NIH HHS R01 AA030042NIMH NIH HHS F31 MH132280NIMH NIH HHS R01 MH107444NIMH NIH HHS R01 MH121409NIMH NIH HHS R01 MH125370NIMH NIH HHS R01 MH131264NIMH NIH HHS T32 MH018921
6 · The paper itself

Abstract

Elevated levels of Neuroticism/Negative Emotionality (N/NE) and, less consistently, lower levels of Extraversion/Positive Emotionality (E/PE) confer risk for pathological depression and anxiety. To date, most prospective-longitudinal research has narrowly focused on traditional diagnostic categories, creating uncertainty about the precise nature of these prospective associations. Adopting an explicitly hierarchical-dimensional approach, we examined the association between baseline variation in personality and longitudinal changes in broad and narrow internalizing-symptom dimensions in 234 emerging adults followed for 2.5 years, during the transition from older adolescence to early adulthood. N/NE was uniquely associated with increases in broadband internalizing-the core cognitive and affective symptoms that cut across the emotional disorders-and unrelated to the narrower dimensions of positive affect and anxious arousal that differentiate specific internalizing presentations. Variation in E/PE and several other Big Five traits was cross-sectionally, but not prospectively, related to longitudinal changes in specific internalizing symptoms. Exploratory personality-facet-level analyses provided preliminary evidence of more granular associations between personality and longitudinal changes in internalizing symptoms. These observations enhance the precision of models linking personality to internalizing illness; highlight the centrality of N/NE to increases in transdiagnostic internalizing symptoms during a key developmental chapter; and set the stage for developing more effective prevention and treatment strategies.

Indexed as

anxietyBig Fivedepressionemerging adulthoodemotional disordersHierarchical Taxonomy of Psychopathology (HiTOP)internalizing illnesspersonality and temperament

Identifiers

PMID39359716
PMCPMC11446481

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.